3rc0: Difference between revisions

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[[Image:3rc0.png|left|200px]]


<!--
==Human SETD6 in complex with RelA Lys310 peptide==
The line below this paragraph, containing "STRUCTURE_3rc0", creates the "Structure Box" on the page.
<StructureSection load='3rc0' size='340' side='right'caption='[[3rc0]], [[Resolution|resolution]] 2.19&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3rc0]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RC0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RC0 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.19&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SAM:S-ADENOSYLMETHIONINE'>SAM</scene></td></tr>
{{STRUCTURE_3rc0|  PDB=3rc0  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rc0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rc0 OCA], [https://pdbe.org/3rc0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rc0 RCSB], [https://www.ebi.ac.uk/pdbsum/3rc0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rc0 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/SETD6_HUMAN SETD6_HUMAN] Protein-lysine N-methyltransferase that specifically monomethylates 'Lys-310' of the RELA subunit of NF-kappa-B complex, leading to down-regulate NF-kappa-B transcription factor activity.<ref>PMID:21131967</ref>


===Human SETD6 in complex with RelA Lys310 peptide===
==See Also==
 
*[[Histone methyltransferase 3D structures|Histone methyltransferase 3D structures]]
 
== References ==
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<references/>
The line below this paragraph, {{ABSTRACT_PUBMED_21515635}}, adds the Publication Abstract to the page
__TOC__
(as it appears on PubMed at http://www.pubmed.gov), where 21515635 is the PubMed ID number.
</StructureSection>
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{{ABSTRACT_PUBMED_21515635}}
 
==About this Structure==
[[3rc0]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RC0 OCA].
 
==Reference==
<ref group="xtra">PMID:021515635</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Chang, Y.]]
[[Category: Large Structures]]
[[Category: Cheng, X.]]
[[Category: Chang Y]]
[[Category: Gozani, O.]]
[[Category: Cheng X]]
[[Category: Horton, J R.]]
[[Category: Gozani O]]
[[Category: Levy, D.]]
[[Category: Horton JR]]
[[Category: Peng, J.]]
[[Category: Levy D]]
[[Category: Zhang, X.]]
[[Category: Peng J]]
[[Category: Epigenetic]]
[[Category: Zhang X]]
[[Category: Protein lysine monomethylation]]
[[Category: Transferase]]

Latest revision as of 12:17, 14 March 2024

Human SETD6 in complex with RelA Lys310 peptide

3rc0, resolution 2.19Å

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