3rdi: Difference between revisions

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[[Image:3rdi.jpg|left|200px]]


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==Domain-domain flexibility leads to allostery within the camp receptor protein (CRP)==
The line below this paragraph, containing "STRUCTURE_3rdi", creates the "Structure Box" on the page.
<StructureSection load='3rdi' size='340' side='right'caption='[[3rdi]], [[Resolution|resolution]] 2.95&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3rdi]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RDI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RDI FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.95&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CMP:ADENOSINE-3,5-CYCLIC-MONOPHOSPHATE'>CMP</scene></td></tr>
{{STRUCTURE_3rdi|  PDB=3rdi  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rdi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rdi OCA], [https://pdbe.org/3rdi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rdi RCSB], [https://www.ebi.ac.uk/pdbsum/3rdi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rdi ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CRP_ECOLI CRP_ECOLI] This protein complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons. The protein induces a severe bend in the DNA. Acts as a negative regulator of its own synthesis as well as for adenylate cyclase (cyaA), which generates cAMP.<ref>PMID:2982847</ref>  


===Domain-domain flexibility leads to allostery within the camp receptor protein (CRP)===
==See Also==
 
*[[Catabolite gene activator protein 3D structures|Catabolite gene activator protein 3D structures]]
 
== References ==
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<references/>
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</StructureSection>
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[[Category: Escherichia coli K-12]]
{{ABSTRACT_PUBMED_2828639}}
[[Category: Large Structures]]
 
[[Category: Knapp J]]
==About this Structure==
[[Category: Lee JC]]
[[3rdi]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RDI OCA].
[[Category: White MA]]
 
==Reference==
<ref group="xtra">PMID:002828639</ref><references group="xtra"/>
[[Category: Escherichia coli]]
[[Category: Knapp, J.]]
[[Category: Lee, J C.]]
[[Category: White, M A.]]
[[Category: Allostery]]
[[Category: Dna binding cyclic amp]]
[[Category: Dna binding protein]]
[[Category: Transcription regulator]]
Retrieved from "https://proteopedia.org/3rdi"