3rnq: Difference between revisions

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[[Image:3rnq.jpg|left|200px]]


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==Crystal structure of the complex between the extracellular domains of mouse PD-1 mutant and PD-L2==
The line below this paragraph, containing "STRUCTURE_3rnq", creates the "Structure Box" on the page.
<StructureSection load='3rnq' size='340' side='right'caption='[[3rnq]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3rnq]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RNQ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RNQ FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rnq FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rnq OCA], [https://pdbe.org/3rnq PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rnq RCSB], [https://www.ebi.ac.uk/pdbsum/3rnq PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rnq ProSAT]</span></td></tr>
{{STRUCTURE_3rnq|  PDB=3rnq  |  SCENE=  }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/PD1L2_MOUSE PD1L2_MOUSE] Involved in the costimulatory signal essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.<ref>PMID:11283156</ref> <ref>PMID:11224527</ref> <ref>PMID:12719480</ref>  


===Crystal structure of the complex between the extracellular domains of mouse PD-1 mutant and PD-L2===
==See Also==
 
*[[Cell death protein 3D structures|Cell death protein 3D structures]]
 
== References ==
==About this Structure==
<references/>
[[3rnq]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RNQ OCA].
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Almo, S C.]]
[[Category: Almo SC]]
[[Category: Lazar-Molnar, E.]]
[[Category: Lazar-Molnar E]]
[[Category: Nathenson, S G.]]
[[Category: Nathenson SG]]
[[Category: Ramagopal, U A.]]
[[Category: Ramagopal UA]]