3s60: Difference between revisions

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[[Image:3s60.png|left|200px]]


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==Structure of the cyanobacterial Oscillatoria Agardhii Agglutinin (OAA) in free state obtained at 25 degree Celsius==
The line below this paragraph, containing "STRUCTURE_3s60", creates the "Structure Box" on the page.
<StructureSection load='3s60' size='340' side='right'caption='[[3s60]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3s60]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Planktothrix_agardhii Planktothrix agardhii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S60 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S60 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s60 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s60 OCA], [https://pdbe.org/3s60 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s60 RCSB], [https://www.ebi.ac.uk/pdbsum/3s60 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s60 ProSAT]</span></td></tr>
{{STRUCTURE_3s60|  PDB=3s60  |  SCENE=  }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/LEC1_PLAAG LEC1_PLAAG] Lectin specific for high mannose N-glycans, recognizes the branched moiety of these glycans. Does not recognize other types of N-glycans or monosaccharides. Agglutinates trypsin-treated rabbit erythrocytes. Does not require divalent cations for activity. Inhibits HIV replication in MT4 cells with an EC(50) of 45 nM. Binds to the HIV envelope glycoprotein gp120.<ref>PMID:10817903</ref> <ref>PMID:17314091</ref>  


===Structure of the cyanobacterial Oscillatoria Agardhii Agglutinin (OAA) in free state obtained at 25 degree Celsius===
==See Also==
 
*[[Agglutinin 3D structures|Agglutinin 3D structures]]
 
== References ==
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</StructureSection>
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[[Category: Large Structures]]
{{ABSTRACT_PUBMED_21827952}}
 
==About this Structure==
[[3s60]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Planktothrix_agardhii Planktothrix agardhii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S60 OCA].
 
==Reference==
<ref group="xtra">PMID:021827952</ref><ref group="xtra">PMID:020961847</ref><references group="xtra"/>
[[Category: Planktothrix agardhii]]
[[Category: Planktothrix agardhii]]
[[Category: Gronenborn, A M.]]
[[Category: Gronenborn AM]]
[[Category: Koharudin, L M.I.]]
[[Category: Koharudin LMI]]
[[Category: Anti-hiv lectin]]
[[Category: Beta barrel like fold]]
[[Category: Carbohydrate]]
[[Category: Protein binding]]