3svm: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
 
(4 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:3svm.png|left|200px]]


<!--
==Human MPP8 - human DNMT3AK47me2 peptide==
The line below this paragraph, containing "STRUCTURE_3svm", creates the "Structure Box" on the page.
<StructureSection load='3svm' size='340' side='right'caption='[[3svm]], [[Resolution|resolution]] 2.31&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3svm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SVM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SVM FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.31&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MLY:N-DIMETHYL-LYSINE'>MLY</scene></td></tr>
{{STRUCTURE_3svm|  PDB=3svm  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3svm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3svm OCA], [https://pdbe.org/3svm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3svm RCSB], [https://www.ebi.ac.uk/pdbsum/3svm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3svm ProSAT]</span></td></tr>
 
</table>
===Human MPP8 - human DNMT3AK47me2 peptide===
== Function ==
 
[https://www.uniprot.org/uniprot/MPP8_HUMAN MPP8_HUMAN] Involved in transcriptional regulation. Specifically recognizes and binds methylated 'Lys-9' of histone H3 (H3K9me) and promotes DNA methylation by recruiting DNMT3A to target CpG sites; these can be situated within the coding region of the gene. Mediates down-regulation of CDH1 expression.<ref>PMID:20871592</ref>  
 
== References ==
<!--
<references/>
The line below this paragraph, {{ABSTRACT_PUBMED_22086334}}, adds the Publication Abstract to the page
__TOC__
(as it appears on PubMed at http://www.pubmed.gov), where 22086334 is the PubMed ID number.
</StructureSection>
-->
{{ABSTRACT_PUBMED_22086334}}
 
==About this Structure==
[[3svm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SVM OCA].  
 
==Reference==
<ref group="xtra">PMID:022086334</ref><references group="xtra"/>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Chang, Y.]]
[[Category: Large Structures]]
[[Category: Cheng, X.]]
[[Category: Chang Y]]
[[Category: Horton, J R.]]
[[Category: Cheng X]]
[[Category: Zhang, X.]]
[[Category: Horton JR]]
[[Category: Chromodomain]]
[[Category: Zhang X]]
[[Category: Dimethylated lysine]]
[[Category: Epigenetic]]
[[Category: Methyl-lysine binding]]
[[Category: Mpp8 chromodomain]]
[[Category: The dimethylated human dnmt3ak47me2 is recognized by the chromodomain of mpp8]]
[[Category: Transferase]]

Latest revision as of 13:09, 14 March 2024

Human MPP8 - human DNMT3AK47me2 peptide

3svm, resolution 2.31Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "https://proteopedia.org/index.php?title=3svm&oldid=4097698"