3sy5: Difference between revisions

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{{STRUCTURE_3sy5|  PDB=3sy5  |  SCENE=  }}
===Crystal structure of the mutant S127A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor 6azaUMP===


==Function==
==Crystal structure of the mutant S127A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor 6azaUMP==
[[http://www.uniprot.org/uniprot/PYRF_METTH PYRF_METTH]] Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).[HAMAP-Rule:MF_01200_A]  
<StructureSection load='3sy5' size='340' side='right'caption='[[3sy5]], [[Resolution|resolution]] 1.32&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[3sy5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus_str._Delta_H Methanothermobacter thermautotrophicus str. Delta H]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SY5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SY5 FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.321&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=UP6:6-AZA+URIDINE+5-MONOPHOSPHATE'>UP6</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3sy5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3sy5 OCA], [https://pdbe.org/3sy5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3sy5 RCSB], [https://www.ebi.ac.uk/pdbsum/3sy5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3sy5 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PYRF_METTH PYRF_METTH] Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP).[HAMAP-Rule:MF_01200_A]


==About this Structure==
==See Also==
[[3sy5]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Methanothermobacter_thermautotrophicus_str._delta_h Methanothermobacter thermautotrophicus str. delta h]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SY5 OCA].
*[[Uridine 5'-monophosphate synthase 3D structures|Uridine 5'-monophosphate synthase 3D structures]]
[[Category: Methanothermobacter thermautotrophicus str. delta h]]
__TOC__
[[Category: Orotidine-5'-phosphate decarboxylase]]
</StructureSection>
[[Category: Almo, S C.]]
[[Category: Large Structures]]
[[Category: Desai, B.]]
[[Category: Methanothermobacter thermautotrophicus str. Delta H]]
[[Category: Fedorov, A A.]]
[[Category: Almo SC]]
[[Category: Fedorov, E V.]]
[[Category: Desai B]]
[[Category: Gerlt, J A.]]
[[Category: Fedorov AA]]
[[Category: Iiams, V.]]
[[Category: Fedorov EV]]
[[Category: 6azaump]]
[[Category: Gerlt JA]]
[[Category: Lyase-inhibitor complex]]
[[Category: Iiams V]]
[[Category: Tim barrel]]

Latest revision as of 13:11, 14 March 2024

Crystal structure of the mutant S127A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor 6azaUMP

3sy5, resolution 1.32Å

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