3t4e: Difference between revisions

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[[Image:3t4e.jpg|left|200px]]


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==1.95 Angstrom Crystal Structure of Shikimate 5-dehydrogenase (AroE) from Salmonella enterica subsp. enterica serovar Typhimurium in Complex with NAD==
The line below this paragraph, containing "STRUCTURE_3t4e", creates the "Structure Box" on the page.
<StructureSection load='3t4e' size='340' side='right'caption='[[3t4e]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3t4e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T4E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T4E FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
{{STRUCTURE_3t4e|  PDB=3t4e  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t4e OCA], [https://pdbe.org/3t4e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t4e RCSB], [https://www.ebi.ac.uk/pdbsum/3t4e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t4e ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/YDIB_SALTY YDIB_SALTY] The actual biological function of YdiB remains unclear, nor is it known whether 3-dehydroshikimate or quinate represents the natural substrate. Catalyzes the reversible NAD-dependent reduction of both 3-dehydroshikimate (DHSA) and 3-dehydroquinate to yield shikimate (SA) and quinate, respectively. It can use both NAD or NADP for catalysis, however it has higher catalytic efficiency with NAD.[HAMAP-Rule:MF_01578]


===1.95 Angstrom Crystal Structure of Shikimate 5-dehydrogenase (AroE) from Salmonella enterica subsp. enterica serovar Typhimurium in Complex with NAD===
==See Also==
 
*[[Shikimate dehydrogenase 3D structures|Shikimate dehydrogenase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
[[3t4e]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_typhimurium Salmonella enterica subsp. enterica serovar typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T4E OCA].
[[Category: Large Structures]]
[[Category: Quinate/shikimate dehydrogenase]]
[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
[[Category: Salmonella enterica subsp. enterica serovar typhimurium]]
[[Category: Anderson WF]]
[[Category: Anderson, W F.]]
[[Category: Dubrovska I]]
[[Category: CSGID, Center for Structural Genomics of Infectious Diseases.]]
[[Category: Halavaty A]]
[[Category: Dubrovska, I.]]
[[Category: Light SH]]
[[Category: Halavaty, A.]]
[[Category: Minasov G]]
[[Category: Light, S H.]]
[[Category: Papazisi L]]
[[Category: Minasov, G.]]
[[Category: Shuvalova L]]
[[Category: Papazisi, L.]]
[[Category: Winsor J]]
[[Category: Shuvalova, L.]]
[[Category: Winsor, J.]]
[[Category: Aminoacid dehydrogenase-like n-terminal domain]]
[[Category: Center for structural genomics of infectious disease]]
[[Category: Csgid]]
[[Category: Nad]]
[[Category: Oxidoreductase]]
[[Category: Structural genomic]]