3t7m: Difference between revisions

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[[Image:3t7m.png|left|200px]]


{{STRUCTURE_3t7m|  PDB=3t7m  |  SCENE=  }}
==Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese and UDP, in a triclinic closed form==
 
<StructureSection load='3t7m' size='340' side='right'caption='[[3t7m]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
===Crystal Structure of Human Glycogenin-1 (GYG1) complexed with manganese and UDP, in a triclinic closed form===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[3t7m]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T7M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T7M FirstGlance]. <br>
{{ABSTRACT_PUBMED_22160680}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t7m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t7m OCA], [https://pdbe.org/3t7m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t7m RCSB], [https://www.ebi.ac.uk/pdbsum/3t7m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t7m ProSAT]</span></td></tr>
[[3t7m]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T7M OCA].  
</table>
== Disease ==
[https://www.uniprot.org/uniprot/GLYG_HUMAN GLYG_HUMAN] Glycogen storage disease due to glycogenin deficiency. The disease is caused by mutations affecting the gene represented in this entry.  The disease is caused by mutations affecting the gene represented in this entry.
== Function ==
[https://www.uniprot.org/uniprot/GLYG_HUMAN GLYG_HUMAN] Self-glucosylates, via an inter-subunit mechanism, to form an oligosaccharide primer that serves as substrate for glycogen synthase.


==See Also==
==See Also==
*[[Glycogenin|Glycogenin]]
*[[Glycogenin|Glycogenin]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:022160680</ref><references group="xtra"/>
[[Category: Glycogenin glucosyltransferase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C H.]]
[[Category: Large Structures]]
[[Category: Bountra, C.]]
[[Category: Arrowsmith CH]]
[[Category: Chaikuad, A.]]
[[Category: Bountra C]]
[[Category: Delft, F von.]]
[[Category: Chaikuad A]]
[[Category: Edwards, A M.]]
[[Category: Edwards AM]]
[[Category: Froese, D S.]]
[[Category: Froese DS]]
[[Category: Krysztofinska, E.]]
[[Category: Krysztofinska E]]
[[Category: Oppermann, U.]]
[[Category: Oppermann U]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Weigelt J]]
[[Category: Weigelt, J.]]
[[Category: Yue WW]]
[[Category: Yue, W W.]]
[[Category: Von Delft F]]
[[Category: Glycogen biosynthesis]]
[[Category: Glycosylation]]
[[Category: Glycosyltransferase]]
[[Category: Sgc]]
[[Category: Structural genomic]]
[[Category: Structural genomics consortium]]
[[Category: Transferase]]