3u2c: Difference between revisions

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[[Image:3u2c.jpg|left|200px]]


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==Aldose reductase in complex with NSAID-type inhibitor at 1.0 A resolution==
The line below this paragraph, containing "STRUCTURE_3u2c", creates the "Structure Box" on the page.
<StructureSection load='3u2c' size='340' side='right'caption='[[3u2c]], [[Resolution|resolution]] 1.00&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)  
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3u2c]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U2C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3U2C FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene>, <scene name='pdbligand=PG5:1-METHOXY-2-[2-(2-METHOXY-ETHOXY]-ETHANE'>PG5</scene>, <scene name='pdbligand=SUZ:[(1Z)-5-FLUORO-2-METHYL-1-{4-[METHYLSULFINYL]BENZYLIDENE}-1H-INDEN-3-YL]ACETIC+ACID'>SUZ</scene></td></tr>
{{STRUCTURE_3u2c|  PDB=3u2c  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3u2c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3u2c OCA], [https://pdbe.org/3u2c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3u2c RCSB], [https://www.ebi.ac.uk/pdbsum/3u2c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3u2c ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ALDR_HUMAN ALDR_HUMAN] Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies.


===Aldose reductase in complex with NSAID-type inhibitor at 1.0 A resolution===
==See Also==
 
*[[Aldose reductase 3D structures|Aldose reductase 3D structures]]
 
__TOC__
==About this Structure==
</StructureSection>
[[3u2c]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3U2C OCA].
 
==Reference==
<ref group="xtra">PMID:021997888</ref><references group="xtra"/>
[[Category: Aldehyde reductase]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Steuber, H.]]
[[Category: Large Structures]]
[[Category: Oxidoreductase]]
[[Category: Steuber H]]
[[Category: Oxidoreductase-oxidoreductase inhibitor complex]]
[[Category: Tim barrel]]

Latest revision as of 13:46, 14 March 2024

Aldose reductase in complex with NSAID-type inhibitor at 1.0 A resolution

3u2c, resolution 1.00Å

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