3yas: Difference between revisions

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[[Image:3yas.png|left|200px]]


<!--
==HYDROXYNITRILE LYASE COMPLEXED WITH ACETONE==
The line below this paragraph, containing "STRUCTURE_3yas", creates the "Structure Box" on the page.
<StructureSection load='3yas' size='340' side='right'caption='[[3yas]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3yas]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Hevea_brasiliensis Hevea brasiliensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3YAS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3YAS FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACN:ACETONE'>ACN</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
{{STRUCTURE_3yas|  PDB=3yas  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3yas FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3yas OCA], [https://pdbe.org/3yas PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3yas RCSB], [https://www.ebi.ac.uk/pdbsum/3yas PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3yas ProSAT]</span></td></tr>
 
</table>
===HYDROXYNITRILE LYASE COMPLEXED WITH ACETONE===
== Function ==
 
[https://www.uniprot.org/uniprot/HNL_HEVBR HNL_HEVBR] Involved in cyanogenesis, the release of HCN from injured tissues. Decomposes a varieties of (R) or (S) cyanohydrins into HCN and the corresponding aldehydes and ketones. The natural substrate of this enzyme is (S)-acetone cyanohydrin.
 
== Evolutionary Conservation ==
<!--
[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_10548044}}, adds the Publication Abstract to the page
Check<jmol>
(as it appears on PubMed at http://www.pubmed.gov), where 10548044 is the PubMed ID number.
  <jmolCheckbox>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ya/3yas_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_10548044}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
[[3yas]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hevea_brasiliensis Hevea brasiliensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3YAS OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3yas ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
<ref group="xtra">PMID:10548044</ref><ref group="xtra">PMID:9094745</ref><ref group="xtra">PMID:8805565</ref><ref group="xtra">PMID:8621461</ref><references group="xtra"/>
</StructureSection>
[[Category: Hevea brasiliensis]]
[[Category: Hevea brasiliensis]]
[[Category: Hydroxynitrilase]]
[[Category: Large Structures]]
[[Category: Gugganig, M.]]
[[Category: Gugganig M]]
[[Category: Kratky, C.]]
[[Category: Kratky C]]
[[Category: Wagner, U G.]]
[[Category: Wagner UG]]
[[Category: Zuegg, J.]]
[[Category: Zuegg J]]
[[Category: Cyanogenesis]]
[[Category: Cyanohydrin formation]]
[[Category: Lyase]]
[[Category: Oxynitrilase]]
Retrieved from "https://proteopedia.org/3yas"