4e5o: Difference between revisions

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[[Image:4e5o.png|left|200px]]


{{STRUCTURE_4e5o|  PDB=4e5o  |  SCENE=  }}
==Crystal structure of mouse thymidylate synthase in complex with dUMP==
 
<StructureSection load='4e5o' size='340' side='right'caption='[[4e5o]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
===Crystal structure of mouse thymidylate synthase in complex with dUMP===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4e5o]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3ihh 3ihh]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E5O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4E5O FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
==About this Structure==
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BU1:1,4-BUTANEDIOL'>BU1</scene>, <scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene></td></tr>
[[4e5o]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=3ihh 3ihh]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E5O OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4e5o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e5o OCA], [https://pdbe.org/4e5o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4e5o RCSB], [https://www.ebi.ac.uk/pdbsum/4e5o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4e5o ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/TYSY_MOUSE TYSY_MOUSE] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway (By similarity).


==See Also==
==See Also==
*[[Thymidylate synthase|Thymidylate synthase]]
*[[Thymidylate synthase 3D structures|Thymidylate synthase 3D structures]]
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Thymidylate synthase]]
[[Category: Ciesla J]]
[[Category: Ciesla, J.]]
[[Category: Dowiercial A]]
[[Category: Dowiercial, A.]]
[[Category: Fraczyk T]]
[[Category: Fraczyk, T.]]
[[Category: Jarmula A]]
[[Category: Jarmula, A.]]
[[Category: Rode W]]
[[Category: Rode, W.]]
[[Category: Rypniewski W]]
[[Category: Rypniewski, W.]]
[[Category: Sokolowska M]]
[[Category: Sokolowska, M.]]
[[Category: Methyltransferase]]
[[Category: Nucleotide biosynthesis]]
[[Category: Protein-ligand complex]]
[[Category: Transferase]]

Latest revision as of 14:53, 14 March 2024

Crystal structure of mouse thymidylate synthase in complex with dUMP

4e5o, resolution 1.70Å

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