4e82: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,328,572 edits
No edit summary
 
(8 intermediate revisions by the same user not shown)
Line 1: Line 1:
[[Image:4e82.jpg|left|200px]]


<!--
==Crystal structure of monomeric variant of human alpha-defensin 5, HD5 (Glu21EMe mutant)==
The line below this paragraph, containing "STRUCTURE_4e82", creates the "Structure Box" on the page.
<StructureSection load='4e82' size='340' side='right'caption='[[4e82]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[4e82]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E82 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4E82 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EME:N-METHYL-L-GLUTAMIC+ACID'>EME</scene></td></tr>
{{STRUCTURE_4e82|  PDB=4e82  |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4e82 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4e82 OCA], [https://pdbe.org/4e82 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4e82 RCSB], [https://www.ebi.ac.uk/pdbsum/4e82 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4e82 ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/DEF5_HUMAN DEF5_HUMAN] Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing.<ref>PMID:12021776</ref> <ref>PMID:15616305</ref> <ref>PMID:17088326</ref>


===Crystal structure of monomeric variant of human alpha-defensin 5, HD5 (Glu21EMe mutant)===
==See Also==
 
*[[Defensin 3D structures|Defensin 3D structures]]
 
== References ==
==About this Structure==
<references/>
[[4e82]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4E82 OCA].
__TOC__
[[Category: Pazgier, M.]]
</StructureSection>
[[Category: Antimicrobial peptide]]
[[Category: Homo sapiens]]
[[Category: Antimicrobial protein]]
[[Category: Large Structures]]
[[Category: Glu21 methylation]]
[[Category: Pazgier M]]
[[Category: Monomeric variant]]
[[Category: Paneth cell]]

Latest revision as of 14:55, 14 March 2024

Crystal structure of monomeric variant of human alpha-defensin 5, HD5 (Glu21EMe mutant)

4e82, resolution 1.70Å

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "https://proteopedia.org/index.php?title=4e82&oldid=4100145"