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{{STRUCTURE_4eaf|  PDB=4eaf  |  SCENE=  }}
===Thymidine phosphorylase from E.coli===


==Function==
==Thymidine phosphorylase from E.coli==
[[http://www.uniprot.org/uniprot/TYPH_ECOLI TYPH_ECOLI]] The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.  
<StructureSection load='4eaf' size='340' side='right'caption='[[4eaf]], [[Resolution|resolution]] 1.55&Aring;' scene=''>
 
== Structural highlights ==
==About this Structure==
<table><tr><td colspan='2'>[[4eaf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EAF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4EAF FirstGlance]. <br>
[[4eaf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli_k-12 Escherichia coli k-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4EAF OCA].  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.55&#8491;</td></tr>
[[Category: Escherichia coli k-12]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
[[Category: Thymidine phosphorylase]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4eaf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4eaf OCA], [https://pdbe.org/4eaf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4eaf RCSB], [https://www.ebi.ac.uk/pdbsum/4eaf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4eaf ProSAT]</span></td></tr>
[[Category: Abramchik, Y A.]]
</table>
[[Category: Esipov, R S.]]
== Function ==
[[Category: Kuranova, I P.]]
[https://www.uniprot.org/uniprot/TYPH_ECOLI TYPH_ECOLI] The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis.
[[Category: Timofeev, V I.]]
__TOC__
[[Category: Thymidine phosphorylase]]
</StructureSection>
[[Category: Transferase]]
[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Abramchik YA]]
[[Category: Esipov RS]]
[[Category: Kuranova IP]]
[[Category: Timofeev VI]]