4enk: Difference between revisions

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[[Image:4enk.jpg|left|200px]]


{{STRUCTURE_4enk|  PDB=4enk  |  SCENE=  }}
==Crystal structure of S. pombe Atl1 in complex with damaged DNA containing O6-propylguanine==
 
<StructureSection load='4enk' size='340' side='right'caption='[[4enk]], [[Resolution|resolution]] 3.04&Aring;' scene=''>
===Crystal structure of S. pombe Atl1 in complex with damaged DNA containing O6-propylguanine===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[4enk]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ENK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4ENK FirstGlance]. <br>
{{ABSTRACT_PUBMED_22658721}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.0445&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=6PO:9-(2-DEOXY-5-O-PHOSPHONO-BETA-D-ERYTHRO-PENTOFURANOSYL)-6-PROPOXY-9H-PURIN-2-AMINE'>6PO</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4enk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4enk OCA], [https://pdbe.org/4enk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4enk RCSB], [https://www.ebi.ac.uk/pdbsum/4enk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4enk ProSAT]</span></td></tr>
[[4enk]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4ENK OCA].  
</table>
 
== Function ==
==Reference==
[https://www.uniprot.org/uniprot/ATL1_SCHPO ATL1_SCHPO] Acts as a DNA damage recognition factor. Required for DNA repair from mutagenic O(6)-alkylguanine adducts. Binds O(6)-alkylguanine lesions providing a signal for other DNA repair pathways.
<ref group="xtra">PMID:022658721</ref><references group="xtra"/>
__TOC__
[[Category: Schizosaccharomyces pombe]]
</StructureSection>
[[Category: Arvai, A S.]]
[[Category: Large Structures]]
[[Category: Tainer, J A.]]
[[Category: Schizosaccharomyces pombe 972h-]]
[[Category: Tubbs, J L.]]
[[Category: Synthetic construct]]
[[Category: Alkylation]]
[[Category: Arvai AS]]
[[Category: Alkyltransferase]]
[[Category: Tainer JA]]
[[Category: Base repair]]
[[Category: Tubbs JL]]
[[Category: Dna]]
[[Category: Dna binding protein-dna complex]]
[[Category: Dna damage]]
[[Category: Dna repair]]
[[Category: Guanine]]
[[Category: Ner]]
[[Category: Nucleotide excision repair]]

Latest revision as of 15:05, 14 March 2024

Crystal structure of S. pombe Atl1 in complex with damaged DNA containing O6-propylguanine

4enk, resolution 3.04Å

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