4f2u: Difference between revisions

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[[Image:4f2u.jpg|left|200px]]


{{STRUCTURE_4f2u| PDB=4f2u | SCENE= }}
==Structure of the N254Y/H258Y double mutant of the Phosphatidylinositol-Specific Phospholipase C from S.aureus==
<StructureSection load='4f2u' size='340' side='right'caption='[[4f2u]], [[Resolution|resolution]] 2.19&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4f2u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_str._Newman Staphylococcus aureus subsp. aureus str. Newman]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F2U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4F2U FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.19&#8491;</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4f2u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f2u OCA], [https://pdbe.org/4f2u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4f2u RCSB], [https://www.ebi.ac.uk/pdbsum/4f2u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4f2u ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PLC_STAAE PLC_STAAE] Cleaves glycosylphosphatidylinositol (GPI) and phosphatidylinositol (PI) anchors but not PI phosphates. Potential virulence factor.


===Structure of the N254Y/H258Y double mutant of the Phosphatidylinositol-Specific Phospholipase C from S.aureus===
==See Also==
 
*[[Phospholipase C|Phospholipase C]]
{{ABSTRACT_PUBMED_23038258}}
__TOC__
 
</StructureSection>
==About this Structure==
[[Category: Large Structures]]
[[4f2u]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_str._newman Staphylococcus aureus subsp. aureus str. newman]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F2U OCA].
[[Category: Staphylococcus aureus subsp. aureus str. Newman]]
[[Category: Phosphatidylinositol diacylglycerol-lyase]]
[[Category: Cheng J]]
[[Category: Staphylococcus aureus subsp. aureus str. newman]]
[[Category: Gershenson A]]
[[Category: Cheng, J.]]
[[Category: Goldstein R]]
[[Category: Gershenson, A.]]
[[Category: Roberts MF]]
[[Category: Goldstein, R.]]
[[Category: Stec B]]
[[Category: Roberts, M F.]]
[[Category: Stec, B.]]
[[Category: Alpha beta barrel]]
[[Category: Lyase]]
[[Category: Membrane interface]]
[[Category: Phosphatidylinositol-specific phospholipase c]]
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