4f4r: Difference between revisions

==Crystal structure of D-mannonate dehydratase homolog from Chromohalobacter salexigens (Target EFI-502114), with bound NA, ordered loop==

<StructureSection load='4f4r' size='340' side='right'caption='[[4f4r]], [[Resolution|resolution]] 1.80&Aring;' scene=''>

== Structural highlights ==

<table><tr><td colspan='2'>[[4f4r]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Chromohalobacter_salexigens_DSM_3043 Chromohalobacter salexigens DSM 3043]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4F4R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4F4R FirstGlance]. <br>

</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>

<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4f4r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4f4r OCA], [https://pdbe.org/4f4r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4f4r RCSB], [https://www.ebi.ac.uk/pdbsum/4f4r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4f4r ProSAT]</span></td></tr>

[https://www.uniprot.org/uniprot/DMGD_CHRSD DMGD_CHRSD] Has low dehydratase activity with D-mannonate and D-gluconate, suggesting that these are not physiological substrates and that it has no significant role in the in vivo degradation of these compounds. Has no detectable activity with a panel of 70 other acid sugars (in vitro).<ref>PMID:24697546</ref>

[[Category: Chromohalobacter salexigens DSM 3043]]

[[Category: Large Structures]]

[[Category: Al Obaidi NF]]

[[Category: Almo SC]]

[[Category: Bhosle R]]

[[Category: Chowdhury S]]

[[Category: Evans B]]

[[Category: Gerlt JA]]

[[Category: Hammonds J]]

[[Category: Hillerich B]]

[[Category: Imker HJ]]

[[Category: Love J]]

[[Category: Morisco LL]]

[[Category: Scott Glenn A]]

[[Category: Seidel RD]]

[[Category: Sojitra S]]

[[Category: Toro R]]

[[Category: Vetting MW]]

[[Category: Washington E]]

[[Category: Wasserman SR]]