4fdl: Difference between revisions

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[[Image:4fdl.png|left|200px]]


{{STRUCTURE_4fdl| PDB=4fdl | SCENE= }}
==Crystal structure of Caspase-7==
<StructureSection load='4fdl' size='340' side='right'caption='[[4fdl]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
<table><tr><td colspan='2'>[[4fdl]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FDL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FDL FirstGlance]. <br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.801&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fdl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fdl OCA], [https://pdbe.org/4fdl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fdl RCSB], [https://www.ebi.ac.uk/pdbsum/4fdl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fdl ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CASP7_HUMAN CASP7_HUMAN] Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death.


===Crystal structure of Caspase-7===
==See Also==
 
*[[Caspase 3D structures|Caspase 3D structures]]
{{ABSTRACT_PUBMED_22795132}}
__TOC__
 
</StructureSection>
==About this Structure==
[[4fdl]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FDL OCA].
 
==Reference==
<ref group="xtra">PMID:022795132</ref><references group="xtra"/>
[[Category: Caspase-7]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Kabaleeswaran, V.]]
[[Category: Large Structures]]
[[Category: Central cavity]]
[[Category: Kabaleeswaran V]]
[[Category: Cysteine protease]]
[[Category: Hydrolase]]
Retrieved from "https://proteopedia.org/4fdl"