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==Crystal Structure of Shikimate Dehydrogenase (aroE) Clinical Variant v2356 from Helicobacter pylori in Complex with Shikimate==
==Crystal Structure of Shikimate Dehydrogenase (aroE) Clinical Variant v2356 from Helicobacter pylori in Complex with Shikimate==
<StructureSection load='4fsh' size='340' side='right' caption='[[4fsh]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
<StructureSection load='4fsh' size='340' side='right'caption='[[4fsh]], [[Resolution|resolution]] 2.85&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4fsh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Campylobacter_pylori Campylobacter pylori]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FSH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4FSH FirstGlance]. <br>
<table><tr><td colspan='2'>[[4fsh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori_26695 Helicobacter pylori 26695]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4FSH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4FSH FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SKM:(3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC+ACID'>SKM</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.85&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3phg|3phg]], [[3phh|3phh]], [[3phi|3phi]], [[3phj|3phj]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SKM:(3R,4S,5R)-3,4,5-TRIHYDROXYCYCLOHEX-1-ENE-1-CARBOXYLIC+ACID'>SKM</scene></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">aroE, HP_1249 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=85962 Campylobacter pylori])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4fsh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fsh OCA], [https://pdbe.org/4fsh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4fsh RCSB], [https://www.ebi.ac.uk/pdbsum/4fsh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4fsh ProSAT]</span></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Shikimate_dehydrogenase Shikimate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.25 1.1.1.25] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4fsh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4fsh OCA], [http://pdbe.org/4fsh PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4fsh RCSB], [http://www.ebi.ac.uk/pdbsum/4fsh PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4fsh ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/AROE_HELPY AROE_HELPY]


==See Also==
==See Also==
*[[Shikimate dehydrogenase|Shikimate dehydrogenase]]
*[[Shikimate dehydrogenase 3D structures|Shikimate dehydrogenase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Campylobacter pylori]]
[[Category: Helicobacter pylori 26695]]
[[Category: Shikimate dehydrogenase]]
[[Category: Large Structures]]
[[Category: Chen, T J]]
[[Category: Chen TJ]]
[[Category: Cheng, W C]]
[[Category: Cheng WC]]
[[Category: Wang, W C]]
[[Category: Wang WC]]
[[Category: Dehydrogenase]]
[[Category: Nadp binding]]
[[Category: Oxidoreductase]]

Latest revision as of 15:33, 14 March 2024

Crystal Structure of Shikimate Dehydrogenase (aroE) Clinical Variant v2356 from Helicobacter pylori in Complex with Shikimate

4fsh, resolution 2.85Å

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