4gd7: Difference between revisions

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~~{{STRUCTURE_4gd7| PDB=4gd7 | SCENE= }}~~

~~===Wild-Type Human Thymidylate Synthase with bound Purpurogallin===~~

==~~Function~~==

==Wild-Type Human Thymidylate Synthase with bound Purpurogallin==

[[http://www.uniprot.org/uniprot/TYSY_HUMAN TYSY_HUMAN]] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway.<ref>PMID:21876188</ref>

== Structural highlights ==

<table><tr><td colspan='2'>[[4gd7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GD7 OCA]. For a guided tour on the structure components use [https://proteopedia.org/fgij/fg.htm?mol=4GD7 FirstGlance].

</td></tr><tr id='method'><td class="sblockLbl">[[Empirical_models|Method:]]</td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.29Å</td></tr>

<tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>, <scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TIY:2,3,4,6-TETRAHYDROXY-5H-BENZO[7]ANNULEN-5-ONE'>TIY</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[https://proteopedia.org/fgij/fg.htm?mol=4gd7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gd7 OCA], [https://pdbe.org/4gd7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gd7 RCSB], [https://www.ebi.ac.uk/pdbsum/4gd7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gd7 ProSAT]</td></tr>

</table>

== Function ==

[https://www.uniprot.org/uniprot/TYSY_HUMAN TYSY_HUMAN] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway.<ref>PMID:21876188</ref>

==~~About this Structure~~==

==See Also==

[[~~4gd7~~]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GD7 OCA].

*[[Thymidylate synthase 3D structures|Thymidylate synthase 3D structures]]

== References ==

==~~Reference~~==

__TOC__

</StructureSection>

[[Category: Homo sapiens]]

[[Category: ~~Thymidylate synthase~~]]

[[Category: Large Structures]]

[[Category: Celeste~~, L R.~~]]

[[Category: Celeste LR]]

[[Category: Lebioda, L~~.]]~~

[[Category: Lebioda L]]

~~[[Category: Methyltransferase]]~~

~~[[Category: Transferase]]~~

~~[[Category: Transferase-transferase inhibitor complex~~]]

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@@ Line 1: / Line 1: @@
-{{STRUCTURE_4gd7|  PDB=4gd7  |  SCENE=  }}
-===Wild-Type Human Thymidylate Synthase with bound Purpurogallin===
-==Function==
+==Wild-Type Human Thymidylate Synthase with bound Purpurogallin==
-[[http://www.uniprot.org/uniprot/TYSY_HUMAN TYSY_HUMAN]] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway.<ref>PMID:21876188</ref>
+<StructureSection load='4gd7' size='340' side='right'caption='[[4gd7]], [[Resolution|resolution]] 2.29&Aring;' scene=''>
+== Structural highlights ==
+<table><tr><td colspan='2'>[[4gd7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GD7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4GD7 FirstGlance]. <br>
+</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.29&#8491;</td></tr>
+<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>, <scene name='pdbligand=CSD:3-SULFINOALANINE'>CSD</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TIY:2,3,4,6-TETRAHYDROXY-5H-BENZO[7]ANNULEN-5-ONE'>TIY</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4gd7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4gd7 OCA], [https://pdbe.org/4gd7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4gd7 RCSB], [https://www.ebi.ac.uk/pdbsum/4gd7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4gd7 ProSAT]</span></td></tr>
+</table>
+== Function ==
+[https://www.uniprot.org/uniprot/TYSY_HUMAN TYSY_HUMAN] Contributes to the de novo mitochondrial thymidylate biosynthesis pathway.<ref>PMID:21876188</ref>
-==About this Structure==
+==See Also==
-[[4gd7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4GD7 OCA].
+*[[Thymidylate synthase 3D structures|Thymidylate synthase 3D structures]]
+== References ==
-==Reference==
+<references/>
-<references group="xtra"/><references/>
+__TOC__
+</StructureSection>
 [[Category: Homo sapiens]]
-[[Category: Thymidylate synthase]]
+[[Category: Large Structures]]
-[[Category: Celeste, L R.]]
+[[Category: Celeste LR]]
-[[Category: Lebioda, L.]]
+[[Category: Lebioda L]]
-[[Category: Methyltransferase]]
-[[Category: Transferase]]
-[[Category: Transferase-transferase inhibitor complex]]