3o7q: Difference between revisions

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{{Seed}}
[[Image:3o7q.jpg|left|200px]]


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==Crystal structure of a Major Facilitator Superfamily (MFS) transporter, FucP, in the outward conformation==
The line below this paragraph, containing "STRUCTURE_3o7q", creates the "Structure Box" on the page.
<StructureSection load='3o7q' size='340' side='right'caption='[[3o7q]], [[Resolution|resolution]] 3.14&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[3o7q]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O7Q OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3O7Q FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.143&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BNG:B-NONYLGLUCOSIDE'>BNG</scene></td></tr>
{{STRUCTURE_3o7q| PDB=3o7q |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3o7q FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3o7q OCA], [https://pdbe.org/3o7q PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3o7q RCSB], [https://www.ebi.ac.uk/pdbsum/3o7q PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3o7q ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/FUCP_ECOLI FUCP_ECOLI] Mediates the uptake of L-fucose across the boundary membrane with the concomitant transport of protons into the cell (symport system). Can also transport L-galactose and D-arabinose, but at reduced rates compared with L-fucose. Is not able to transport L-rhamnose and L-arabinose.<ref>PMID:2829831</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/o7/3o7q_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3o7q ConSurf].
<div style="clear:both"></div>


===Crystal structure of a Major Facilitator Superfamily (MFS) transporter, FucP, in the outward conformation===
==See Also==
 
*[[Lactose Permease|Lactose Permease]]
 
*[[Symporter 3D structures|Symporter 3D structures]]
==About this Structure==
== References ==
3O7Q is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3O7Q OCA].
<references/>
[[Category: Escherichia coli]]
__TOC__
[[Category: Dang, S Y.]]
</StructureSection>
[[Category: Sun, L F.]]
[[Category: Escherichia coli K-12]]
[[Category: Wang, J.]]
[[Category: Large Structures]]
[[Category: Yan, N.]]
[[Category: Dang SY]]
[[Category: L-fucose]]
[[Category: Sun LF]]
[[Category: Multi-pass membrane protein]]
[[Category: Wang J]]
[[Category: Symporter]]
[[Category: Yan N]]
[[Category: Transport protein]]
[[Category: Transporter]]
 
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