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[[Image:1eud.png|left|200px]]


{{STRUCTURE_1eud|  PDB=1eud  |  SCENE=  }}
==CRYSTAL STRUCTURE OF PHOSPHORYLATED PIG HEART, GTP-SPECIFIC SUCCINYL-COA SYNTHETASE==
 
<StructureSection load='1eud' size='340' side='right'caption='[[1eud]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
===CRYSTAL STRUCTURE OF PHOSPHORYLATED PIG HEART, GTP-SPECIFIC SUCCINYL-COA SYNTHETASE===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1eud]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EUD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EUD FirstGlance]. <br>
{{ABSTRACT_PUBMED_10873456}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene>, <scene name='pdbligand=CSS:S-MERCAPTOCYSTEINE'>CSS</scene>, <scene name='pdbligand=NEP:N1-PHOSPHONOHISTIDINE'>NEP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1eud FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1eud OCA], [https://pdbe.org/1eud PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1eud RCSB], [https://www.ebi.ac.uk/pdbsum/1eud PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1eud ProSAT]</span></td></tr>
[[1eud]] is a 2 chain structure of [[Succinyl-CoA synthetase]] with sequence from [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EUD OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/SUCA_PIG SUCA_PIG] Catalyzes the ATP- or GTP-dependent ligation of succinate and CoA to form succinyl-CoA. The nature of the beta subunit determines the nucleotide specificity (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/eu/1eud_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1eud ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Succinyl-CoA synthetase|Succinyl-CoA synthetase]]
*[[Succinyl-CoA synthetase 3D structures|Succinyl-CoA synthetase 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:010873456</ref><references group="xtra"/>
[[Category: Large Structures]]
[[Category: Sus scrofa]]
[[Category: Sus scrofa]]
[[Category: Bridger, W A.]]
[[Category: Bridger WA]]
[[Category: Fraser, M E.]]
[[Category: Fraser ME]]
[[Category: James, M N.G.]]
[[Category: James MNG]]
[[Category: Wolodko, W T.]]
[[Category: Wolodko WT]]
[[Category: Gtp-specific]]
[[Category: Ligase]]
[[Category: Phosphonohistidine]]

Latest revision as of 10:06, 20 March 2024

CRYSTAL STRUCTURE OF PHOSPHORYLATED PIG HEART, GTP-SPECIFIC SUCCINYL-COA SYNTHETASE

1eud, resolution 2.10Å

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