1f58: Difference between revisions

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[[Image:1f58.png|left|200px]]


{{STRUCTURE_1f58|  PDB=1f58  |  SCENE=  }}
==IGG1 FAB FRAGMENT (58.2) COMPLEX WITH 24-RESIDUE PEPTIDE (RESIDUES 308-333 OF HIV-1 GP120 (MN ISOLATE) WITH ALA TO AIB SUBSTITUTION AT POSITION 323==
 
<StructureSection load='1f58' size='340' side='right'caption='[[1f58]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
===IGG1 FAB FRAGMENT (58.2) COMPLEX WITH 24-RESIDUE PEPTIDE (RESIDUES 308-333 OF HIV-1 GP120 (MN ISOLATE) WITH ALA TO AIB SUBSTITUTION AT POSITION 323===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1f58]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/HIV-1_M:B_MN HIV-1 M:B_MN] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F58 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1F58 FirstGlance]. <br>
{{ABSTRACT_PUBMED_10368281}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AIB:ALPHA-AMINOISOBUTYRIC+ACID'>AIB</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1f58 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1f58 OCA], [https://pdbe.org/1f58 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1f58 RCSB], [https://www.ebi.ac.uk/pdbsum/1f58 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1f58 ProSAT]</span></td></tr>
[[1f58]] is a 3 chain structure of [[Antibody]] with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1F58 OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/KV3AE_MOUSE KV3AE_MOUSE]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/f5/1f58_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1f58 ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Antibody|Antibody]]
*[[Antibody 3D structures|Antibody 3D structures]]
 
*[[3D structures of non-human antibody|3D structures of non-human antibody]]
==Reference==
__TOC__
<ref group="xtra">PMID:010368281</ref><ref group="xtra">PMID:011599031</ref><references group="xtra"/>
</StructureSection>
[[Category: HIV-1 M:B_MN]]
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Cabezas, E.]]
[[Category: Cabezas E]]
[[Category: Profy, A T.]]
[[Category: Profy AT]]
[[Category: Satterthwait, A C.]]
[[Category: Satterthwait AC]]
[[Category: Stanfield, R L.]]
[[Category: Stanfield RL]]
[[Category: Stura, E A.]]
[[Category: Stura EA]]
[[Category: Wilson, I A.]]
[[Category: Wilson IA]]
[[Category: Fab]]
[[Category: Gp120]]
[[Category: Hiv-1]]
[[Category: Immunoglobulin]]
[[Category: V3]]
[[Category: Viral protein-immune system complex]]
Retrieved from "https://proteopedia.org/1f58"