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[[Image:2zit.png|left|200px]]


{{STRUCTURE_2zit|  PDB=2zit  |  SCENE=  }}
==Structure of the eEF2-ExoA-NAD+ complex==
 
<StructureSection load='2zit' size='340' side='right'caption='[[2zit]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
===Structure of the eEF2-ExoA-NAD+ complex===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2zit]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa] and [https://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZIT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2ZIT FirstGlance]. <br>
{{ABSTRACT_PUBMED_18583986}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DDE:{3-[4-(2-AMINO-2-CARBOXY-ETHYL)-1H-IMIDAZOL-2-YL]-1-CARBAMOYL-PROPYL}-TRIMETHYL-AMMONIUM'>DDE</scene>, <scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2zit FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2zit OCA], [https://pdbe.org/2zit PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2zit RCSB], [https://www.ebi.ac.uk/pdbsum/2zit PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2zit ProSAT]</span></td></tr>
[[2zit]] is a 6 chain structure with sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa] and [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ZIT OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/EF2_YEAST EF2_YEAST]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/zi/2zit_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2zit ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Elongation factor|Elongation factor]]
*[[Elongation factor 3D structures|Elongation factor 3D structures]]
 
*[[Exotoxin 3D structures|Exotoxin 3D structures]]
==Reference==
__TOC__
<ref group="xtra">PMID:018583986</ref><references group="xtra"/>
</StructureSection>
[[Category: Large Structures]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Pseudomonas aeruginosa]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Jorgensen, R.]]
[[Category: Jorgensen R]]
[[Category: Merrill, A R.]]
[[Category: Merrill AR]]
[[Category: Adp-ribosylation]]
[[Category: Biosynthetic protein-transferase complex]]
[[Category: Elongation factor]]
[[Category: Glycosyltransferase]]
[[Category: Gtp-binding]]
[[Category: Nad]]
[[Category: Nucleotide-binding]]
[[Category: Phosphoprotein]]
[[Category: Protein biosynthesis]]
[[Category: Rna-binding]]
[[Category: Rrna-binding]]
[[Category: Toxin]]
[[Category: Toxin-substrate complex]]
[[Category: Transferase]]

Latest revision as of 06:33, 3 April 2024

Structure of the eEF2-ExoA-NAD+ complex

2zit, resolution 3.00Å

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