3nto: Difference between revisions
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== | ==Crystal structure of K97V mutant myo-inositol dehydrogenase from Bacillus subtilis== | ||
[[3nto]] is a 1 chain structure with sequence from [ | <StructureSection load='3nto' size='340' side='right'caption='[[3nto]], [[Resolution|resolution]] 1.91Å' scene=''> | ||
== Structural highlights == | |||
== | <table><tr><td colspan='2'>[[3nto]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3NTO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3NTO FirstGlance]. <br> | ||
< | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9124Å</td></tr> | ||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EPE:4-(2-HYDROXYETHYL)-1-PIPERAZINE+ETHANESULFONIC+ACID'>EPE</scene></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3nto FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3nto OCA], [https://pdbe.org/3nto PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3nto RCSB], [https://www.ebi.ac.uk/pdbsum/3nto PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3nto ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/IOLG_BACSU IOLG_BACSU] Involved in the oxidation of myo-inositol (MI) and D-chiro-inositol (DCI) to 2-keto-myo-inositol (2KMI or 2-inosose) and 1-keto-D-chiro-inositol (1KDCI), respectively. Can also use D-glucose and D-xylose, and shows a trace of activity with D-ribose and D-fructose.<ref>PMID:112095</ref> <ref>PMID:16461681</ref> | |||
== Evolutionary Conservation == | |||
[[Image:Consurf_key_small.gif|200px|right]] | |||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/nt/3nto_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=3nto ConSurf]. | |||
<div style="clear:both"></div> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Bacillus subtilis]] | [[Category: Bacillus subtilis]] | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: Palmer | [[Category: Palmer DRJ]] | ||
[[Category: Sanders | [[Category: Sanders DAR]] | ||
[[Category: Straaten | [[Category: Van Straaten KE]] | ||
Latest revision as of 06:42, 3 April 2024
Crystal structure of K97V mutant myo-inositol dehydrogenase from Bacillus subtilis
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