8d8i: Difference between revisions

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'''Unreleased structure'''


The entry 8d8i is ON HOLD
==Crystal structure of Reverb alpha in complex with synthetic agonist==
 
<StructureSection load='8d8i' size='340' side='right'caption='[[8d8i]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
Authors:  
== Structural highlights ==
 
<table><tr><td colspan='2'>[[8d8i]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8D8I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8D8I FirstGlance]. <br>
Description:  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.504&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=QFX:(4S)-6-[([1,1-biphenyl]-2-yl)oxy]-3-chloro[1,2,4]triazolo[4,3-b]pyridazine'>QFX</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8d8i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8d8i OCA], [https://pdbe.org/8d8i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8d8i RCSB], [https://www.ebi.ac.uk/pdbsum/8d8i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8d8i ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/NR1D1_HUMAN NR1D1_HUMAN] Functions as a constitutive transcriptional repressor. In collaboration with SP1, activates GJA1 transcription (By similarity). Possible receptor for triiodothyronine.<ref>PMID:2539258</ref> <ref>PMID:1971514</ref>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Burris PT]]
[[Category: Ciesielski F]]
[[Category: Hegazy L]]
[[Category: Ronin C]]
Retrieved from "https://proteopedia.org/8d8i"