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[[Image:1lek.png|left|200px]]


{{STRUCTURE_1lek|  PDB=1lek  |  SCENE=  }}
==Crystal Structure of H-2Kbm3 bound to dEV8==
 
<StructureSection load='1lek' size='340' side='right'caption='[[1lek]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
===Crystal Structure of H-2Kbm3 bound to dEV8===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1lek]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LEK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1LEK FirstGlance]. <br>
{{ABSTRACT_PUBMED_11994422}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
 
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
==About this Structure==
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1lek FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1lek OCA], [https://pdbe.org/1lek PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1lek RCSB], [https://www.ebi.ac.uk/pdbsum/1lek PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1lek ProSAT]</span></td></tr>
[[1lek]] is a 3 chain structure of [[Beta-2 microglobulin]] and [[Major histocompatibility complex]] with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1LEK OCA].  
</table>
== Function ==
[https://www.uniprot.org/uniprot/HA1B_MOUSE HA1B_MOUSE] Involved in the presentation of foreign antigens to the immune system.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/le/1lek_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1lek ConSurf].
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Beta-2 microglobulin|Beta-2 microglobulin]]
*[[Beta-2 microglobulin 3D structures|Beta-2 microglobulin 3D structures]]
*[[Major histocompatibility complex|Major histocompatibility complex]]
*[[MHC 3D structures|MHC 3D structures]]
 
*[[MHC I 3D structures|MHC I 3D structures]]
==Reference==
__TOC__
<ref group="xtra">PMID:011994422</ref><references group="xtra"/>
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Apostolopoulos, V.]]
[[Category: Apostolopoulos V]]
[[Category: Garcia, K C.]]
[[Category: Garcia KC]]
[[Category: Huang, M.]]
[[Category: Huang M]]
[[Category: Luz, J G.]]
[[Category: Luz JG]]
[[Category: Rudolph, M G.]]
[[Category: Rudolph MG]]
[[Category: Teyton, L.]]
[[Category: Teyton L]]
[[Category: Wilson, I A.]]
[[Category: Wilson IA]]
[[Category: Immune system]]
[[Category: Mhc class i allogeneic complex with peptide]]
Retrieved from "https://proteopedia.org/1lek"