1md7: Difference between revisions
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==Monomeric structure of the zymogen of complement protease C1r== | |||
<StructureSection load='1md7' size='340' side='right'caption='[[1md7]], [[Resolution|resolution]] 3.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[1md7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MD7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MD7 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |||
== | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1md7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1md7 OCA], [https://pdbe.org/1md7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1md7 RCSB], [https://www.ebi.ac.uk/pdbsum/1md7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1md7 ProSAT]</span></td></tr> | ||
[[1md7]] is a 1 chain structure with sequence from [ | </table> | ||
== Function == | |||
== | [https://www.uniprot.org/uniprot/C1R_HUMAN C1R_HUMAN] C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system. | ||
< | == Evolutionary Conservation == | ||
[[ | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | |||
<jmolCheckbox> | |||
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/md/1md7_consurf.spt"</scriptWhenChecked> | |||
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | |||
<text>to colour the structure by Evolutionary Conservation</text> | |||
</jmolCheckbox> | |||
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1md7 ConSurf]. | |||
<div style="clear:both"></div> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
[[Category: Arlaud | [[Category: Large Structures]] | ||
[[Category: Budayova-Spano | [[Category: Arlaud GJ]] | ||
[[Category: Fontecilla-Camps | [[Category: Budayova-Spano M]] | ||
[[Category: Gaboriaud | [[Category: Fontecilla-Camps J]] | ||
[[Category: Grabarse | [[Category: Gaboriaud C]] | ||
[[Category: Hillen | [[Category: Grabarse W]] | ||
[[Category: Lacroix | [[Category: Hillen H]] | ||
[[Category: Schmidt | [[Category: Lacroix M]] | ||
[[Category: Thielens | [[Category: Schmidt M]] | ||
[[Category: Thielens NM]] | |||
Latest revision as of 08:34, 10 April 2024
Monomeric structure of the zymogen of complement protease C1r
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