1md7: Difference between revisions

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{{Seed}}
[[Image:1md7.png|left|200px]]


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==Monomeric structure of the zymogen of complement protease C1r==
The line below this paragraph, containing "STRUCTURE_1md7", creates the "Structure Box" on the page.
<StructureSection load='1md7' size='340' side='right'caption='[[1md7]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1md7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MD7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1MD7 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
{{STRUCTURE_1md7|  PDB=1md7  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1md7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1md7 OCA], [https://pdbe.org/1md7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1md7 RCSB], [https://www.ebi.ac.uk/pdbsum/1md7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1md7 ProSAT]</span></td></tr>
 
</table>
===Monomeric structure of the zymogen of complement protease C1r===
== Function ==
 
[https://www.uniprot.org/uniprot/C1R_HUMAN C1R_HUMAN] C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system.
 
== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
The line below this paragraph, {{ABSTRACT_PUBMED_12429092}}, adds the Publication Abstract to the page
Check<jmol>
(as it appears on PubMed at http://www.pubmed.gov), where 12429092 is the PubMed ID number.
  <jmolCheckbox>
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    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/md/1md7_consurf.spt"</scriptWhenChecked>
{{ABSTRACT_PUBMED_12429092}}
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 
    <text>to colour the structure by Evolutionary Conservation</text>
==About this Structure==
  </jmolCheckbox>
1MD7 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1MD7 OCA].  
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1md7 ConSurf].
 
<div style="clear:both"></div>
==Reference==
__TOC__
<ref group="xtra">PMID:12429092</ref><references group="xtra"/>
</StructureSection>
[[Category: Complement subcomponent C1r]]
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arlaud, G J.]]
[[Category: Large Structures]]
[[Category: Budayova-Spano, M.]]
[[Category: Arlaud GJ]]
[[Category: Fontecilla-Camps, J.]]
[[Category: Budayova-Spano M]]
[[Category: Gaboriaud, C.]]
[[Category: Fontecilla-Camps J]]
[[Category: Grabarse, W.]]
[[Category: Gaboriaud C]]
[[Category: Hillen, H.]]
[[Category: Grabarse W]]
[[Category: Lacroix, M.]]
[[Category: Hillen H]]
[[Category: Schmidt, M.]]
[[Category: Lacroix M]]
[[Category: Thielens, N M.]]
[[Category: Schmidt M]]
[[Category: Activation]]
[[Category: Thielens NM]]
[[Category: Complement]]
[[Category: Innate immunity]]
[[Category: Serine protease]]
[[Category: Substrate specificity]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 21:26:56 2009''
Retrieved from "https://proteopedia.org/1md7"