1q2e: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
 
(10 intermediate revisions by the same user not shown)
Line 1: Line 1:
{{Seed}}
[[Image:1q2e.png|left|200px]]


<!--
==CELLOBIOHYDROLASE CEL7A WITH LOOP DELETION 245-252 AND BOUND NON-HYDROLYSABLE CELLOTETRAOSE==
The line below this paragraph, containing "STRUCTURE_1q2e", creates the "Structure Box" on the page.
<StructureSection load='1q2e' size='340' side='right'caption='[[1q2e]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1q2e]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trichoderma_reesei Trichoderma reesei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q2E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1Q2E FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=MGL:O1-METHYL-GLUCOSE'>MGL</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene>, <scene name='pdbligand=SGC:4-DEOXY-4-THIO-BETA-D-GLUCOPYRANOSE'>SGC</scene></td></tr>
{{STRUCTURE_1q2e| PDB=1q2e |  SCENE= }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1q2e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1q2e OCA], [https://pdbe.org/1q2e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1q2e RCSB], [https://www.ebi.ac.uk/pdbsum/1q2e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1q2e ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/GUX1_HYPJE GUX1_HYPJE] The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the dissaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose.
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/q2/1q2e_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1q2e ConSurf].
<div style="clear:both"></div>


===CELLOBIOHYDROLASE CEL7A WITH LOOP DELETION 245-252 AND BOUND NON-HYDROLYSABLE CELLOTETRAOSE===
==See Also==
 
*[[Cellobiohydrolase 3D structures|Cellobiohydrolase 3D structures]]
 
*[[Glucanase 3D structures|Glucanase 3D structures]]
<!--
__TOC__
The line below this paragraph, {{ABSTRACT_PUBMED_14568538}}, adds the Publication Abstract to the page
</StructureSection>
(as it appears on PubMed at http://www.pubmed.gov), where 14568538 is the PubMed ID number.
[[Category: Large Structures]]
-->
[[Category: Trichoderma reesei]]
{{ABSTRACT_PUBMED_14568538}}
[[Category: Harris M]]
 
[[Category: Jones TA]]
==About this Structure==
[[Category: Stahlberg J]]
1Q2E is a 2 chains structure of sequences from [http://en.wikipedia.org/wiki/Hypocrea_jecorina Hypocrea jecorina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1Q2E OCA].
 
==Reference==
<ref group="xtra">PMID:14568538</ref><references group="xtra"/>
[[Category: Cellulose 1,4-beta-cellobiosidase]]
[[Category: Hypocrea jecorina]]
[[Category: Harris, M.]]
[[Category: Jones, T A.]]
[[Category: Stahlberg, J.]]
[[Category: Cellotetraose]]
[[Category: Cellulase]]
[[Category: Cellulose degradation]]
[[Category: Glycoprotein]]
[[Category: Glycosidase]]
[[Category: Glycosylated protein]]
[[Category: Hydrolase]]
[[Category: Loop deletion]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Feb 17 09:18:25 2009''
Retrieved from "https://proteopedia.org/1q2e"