2c7i: Difference between revisions

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[[Image:2c7i.png|left|200px]]


{{STRUCTURE_2c7i|  PDB=2c7i  |  SCENE= }}
==Structure of protein Ta0514, putative lipoate protein ligase from T. acidophilum.==
 
<StructureSection load='2c7i' size='340' side='right'caption='[[2c7i]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
===STRUCTURE OF PROTEIN TA0514, PUTATIVE LIPOATE PROTEIN LIGASE FROM T. ACIDOPHILUM.===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[2c7i]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermoplasma_acidophilum_DSM_1728 Thermoplasma acidophilum DSM 1728]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C7I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2C7I FirstGlance]. <br>
{{ABSTRACT_PUBMED_16384580}}
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
 
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2c7i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c7i OCA], [https://pdbe.org/2c7i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2c7i RCSB], [https://www.ebi.ac.uk/pdbsum/2c7i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2c7i ProSAT]</span></td></tr>
==About this Structure==
</table>
[[2c7i]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermoplasma_acidophilum Thermoplasma acidophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2C7I OCA].  
== Function ==
 
[https://www.uniprot.org/uniprot/LPLAN_THEAC LPLAN_THEAC] Part of a lipoate-protein ligase complex that catalyzes both the ATP-dependent activation of exogenously supplied lipoate to lipoyl-AMP and the transfer of the activated lipoyl onto the lipoyl domains of lipoate-dependent enzymes. Can also use octanoate as substrate.<ref>PMID:16141198</ref> <ref>PMID:19520844</ref> <ref>PMID:19594830</ref>  
==Reference==
== Evolutionary Conservation ==
<ref group="xtra">PMID:016384580</ref><references group="xtra"/>
[[Image:Consurf_key_small.gif|200px|right]]
[[Category: Thermoplasma acidophilum]]
Check<jmol>
[[Category: Luisi, B F.]]
  <jmolCheckbox>
[[Category: Mcmanus, E.]]
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/c7/2c7i_consurf.spt"</scriptWhenChecked>
[[Category: Perham, R N.]]
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
[[Category: Ligase]]
    <text>to colour the structure by Evolutionary Conservation</text>
[[Category: Lipoylation]]
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2c7i ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Thermoplasma acidophilum DSM 1728]]
[[Category: Luisi BF]]
[[Category: Mcmanus E]]
[[Category: Perham RN]]