2kr3: Difference between revisions

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[[Image:2kr3.png|left|200px]]


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==Solution structure of SHA-D==
The line below this paragraph, containing "STRUCTURE_2kr3", creates the "Structure Box" on the page.
<StructureSection load='2kr3' size='340' side='right'caption='[[2kr3]]' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2kr3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KR3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KR3 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kr3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kr3 OCA], [https://pdbe.org/2kr3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kr3 RCSB], [https://www.ebi.ac.uk/pdbsum/2kr3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kr3 ProSAT]</span></td></tr>
{{STRUCTURE_2kr3|  PDB=2kr3  |  SCENE=  }}
</table>
 
== Function ==
===Solution structure of SHA-D===
[https://www.uniprot.org/uniprot/SPTN1_CHICK SPTN1_CHICK] Morphologically, spectrin-like proteins appear to be related to spectrin, showing a flexible rod-like structure. They can bind actin but seem to differ in their calmodulin-binding activity. In nonerythroid tissues, spectrins, in association with some other proteins, may play an important role in membrane organization.
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
The line below this paragraph, {{ABSTRACT_PUBMED_20823919}}, adds the Publication Abstract to the page
  <jmolCheckbox>
(as it appears on PubMed at http://www.pubmed.gov), where 20823919 is the PubMed ID number.
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/kr/2kr3_consurf.spt"</scriptWhenChecked>
-->
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
{{ABSTRACT_PUBMED_20823919}}
    <text>to colour the structure by Evolutionary Conservation</text>
 
  </jmolCheckbox>
==About this Structure==
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2kr3 ConSurf].
[[2kr3]] is a 1 chain structure of [[Spectrin]] with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KR3 OCA].  
<div style="clear:both"></div>


==See Also==
==See Also==
*[[Spectrin]]
*[[Spectrin 3D structures|Spectrin 3D structures]]
 
__TOC__
==Reference==
</StructureSection>
<ref group="xtra">PMID:20823919</ref><ref group="xtra">PMID:11478866</ref><references group="xtra"/>
[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
[[Category: Filimonov, V V.]]
[[Category: Large Structures]]
[[Category: Gushchina, L V.]]
[[Category: Filimonov VV]]
[[Category: Khristoforov, V S.]]
[[Category: Gushchina LV]]
[[Category: Kudrevatykh, Y A.]]
[[Category: Khristoforov VS]]
[[Category: Kutyshenko, V P.]]
[[Category: Kudrevatykh YA]]
[[Category: Prokhorov, D A.]]
[[Category: Kutyshenko VP]]
[[Category: Timchenko, M A.]]
[[Category: Prokhorov DA]]
[[Category: Actin capping]]
[[Category: Timchenko MA]]
[[Category: Actin-binding]]
[[Category: Alpha spectrin sh3 domain]]
[[Category: Bergerac]]
[[Category: Cytoskeleton]]
[[Category: Signaling protein]]

Latest revision as of 06:47, 1 May 2024

Solution structure of SHA-D

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