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==Solution-state structure of an intramolecular G-quadruplex with propeller, diagonal and edgewise loops==
==Solution-state structure of an intramolecular G-quadruplex with propeller, diagonal and edgewise loops==
<StructureSection load='2lod' size='340' side='right' caption='[[2lod]], [[NMR_Ensembles_of_Models | 10 NMR models]]' scene=''>
<StructureSection load='2lod' size='340' side='right'caption='[[2lod]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2lod]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LOD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LOD FirstGlance]. <br>
<table><tr><td colspan='2'>[[2lod]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LOD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LOD FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2lod FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lod OCA], [http://pdbe.org/2lod PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2lod RCSB], [http://www.ebi.ac.uk/pdbsum/2lod PDBsum]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lod FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lod OCA], [https://pdbe.org/2lod PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lod RCSB], [https://www.ebi.ac.uk/pdbsum/2lod PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lod ProSAT]</span></td></tr>
</table>
</table>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
We herein report on the formation and high-resolution NMR solution-state structure determination of a G-quadruplex adopted by d[G(3)ATG(3)ACACAG(4)ACG(3)] comprised of four G-tracts with the third one consisting of four guanines that are intervened with non-G streches of different lengths. A single intramolecular antiparallel (3+1) G-quadruplex exhibits three stacked G-quartets connected with propeller, diagonal and edgewise loops of different lengths. The propeller and edgewise loops are well structured, whereas the longer diagonal loop is more flexible. To the best of our knowledge, this is the first high-resolution G-quadruplex structure where all of the three main loop types are present.
Solution-state structure of an intramolecular G-quadruplex with propeller, diagonal and edgewise loops.,Marusic M, Sket P, Bauer L, Viglasky V, Plavec J Nucleic Acids Res. 2012 Apr 24. PMID:22532609<ref>PMID:22532609</ref>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 2lod" style="background-color:#fffaf0;"></div>
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bauer, L]]
[[Category: Large Structures]]
[[Category: Marusic, M]]
[[Category: Bauer L]]
[[Category: Plavec, J]]
[[Category: Marusic M]]
[[Category: Sket, P]]
[[Category: Plavec J]]
[[Category: Viglasky, V]]
[[Category: Sket P]]
[[Category: Dna]]
[[Category: Viglasky V]]
[[Category: G-quadruplex]]
[[Category: Loop]]

Latest revision as of 06:56, 1 May 2024

Solution-state structure of an intramolecular G-quadruplex with propeller, diagonal and edgewise loops

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