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==Solution structure of a parallel-stranded oligoisoguanine DNA pentaplex formed by d(T(iG)4T) in the presence of Cs ions==
==Solution structure of a parallel-stranded oligoisoguanine DNA pentaplex formed by d(T(iG)4T) in the presence of Cs ions==
<StructureSection load='2luj' size='340' side='right' caption='[[2luj]], [[NMR_Ensembles_of_Models | 16 NMR models]]' scene=''>
<StructureSection load='2luj' size='340' side='right'caption='[[2luj]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2luj]] is a 5 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LUJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2LUJ FirstGlance]. <br>
<table><tr><td colspan='2'>[[2luj]] is a 5 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LUJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LUJ FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=0UH:2-DEOXY-2-OXOADENOSINE+5-(DIHYDROGEN+PHOSPHATE)'>0UH</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2luj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2luj OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2luj RCSB], [http://www.ebi.ac.uk/pdbsum/2luj PDBsum]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IGU:2-DEOXYISOGUANINE-5-MONOPHOSPHATE'>IGU</scene></td></tr>
<table>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2luj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2luj OCA], [https://pdbe.org/2luj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2luj RCSB], [https://www.ebi.ac.uk/pdbsum/2luj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2luj ProSAT]</span></td></tr>
<div style="background-color:#fffaf0;">
</table>
== Publication Abstract from PubMed ==
What a pentaplexing situation: Isoguanine (iG) is an isomer of guanine, where the positions of the C2 amino group and the C6 carboxy group are swapped. iG can self-assemble into pentads in the presence of alkali metal cations. Cs(+) ions were found to stabilize a pentaplex of d(T(iG)(4) T). Solution NMR studies of this pentaplex in the presence of Cs(+) ions (or Na(+) , K(+) , Rb(+) , or NH(4) (+) cations) demonstrate its stability and structure.
 
Solution Structure of a Parallel-Stranded Oligoisoguanine DNA Pentaplex Formed by d(T(iG)(4) T) in the Presence of Cs(+) Ions.,Kang M, Heuberger B, Chaput JC, Switzer C, Feigon J Angew Chem Int Ed Engl. 2012 Jul 5. doi: 10.1002/anie.201203459. PMID:22767484<ref>PMID:22767484</ref>
 
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Chaput, J C.]]
[[Category: Large Structures]]
[[Category: Feigon, J.]]
[[Category: Chaput JC]]
[[Category: Heuberger, B.]]
[[Category: Feigon J]]
[[Category: Kang, M.]]
[[Category: Heuberger B]]
[[Category: Switzer, C.]]
[[Category: Kang M]]
[[Category: Dna]]
[[Category: Switzer C]]
[[Category: Isoguanine]]
[[Category: Parallel-stranded]]
[[Category: Pentaplex]]

Latest revision as of 06:57, 1 May 2024

Solution structure of a parallel-stranded oligoisoguanine DNA pentaplex formed by d(T(iG)4T) in the presence of Cs ions

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