2xig: Difference between revisions
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==The structure of the Helicobacter pylori ferric uptake regulator Fur reveals three functional metal binding sites== | |||
<StructureSection load='2xig' size='340' side='right'caption='[[2xig]], [[Resolution|resolution]] 1.85Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2xig]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Helicobacter_pylori_26695 Helicobacter pylori 26695]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XIG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XIG FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85Å</td></tr> | |||
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
'' | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xig FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xig OCA], [https://pdbe.org/2xig PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xig RCSB], [https://www.ebi.ac.uk/pdbsum/2xig PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xig ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/FUR_HELPY FUR_HELPY] Acts as a global negative controlling element, employing Fe(2+) as a cofactor to bind the operator of the repressed genes. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Helicobacter pylori 26695]] | |||
[[Category: Large Structures]] | |||
[[Category: Bahlawane C]] | |||
[[Category: Dian C]] | |||
[[Category: Fauquant F]] | |||
[[Category: Leonard GA]] | |||
[[Category: Michaud-Soret I]] | |||
[[Category: Muller C]] | |||
[[Category: Terradot L]] | |||
[[Category: Vitale S]] | |||
[[Category: De Reuse H]] | |||
Latest revision as of 07:11, 1 May 2024
The structure of the Helicobacter pylori ferric uptake regulator Fur reveals three functional metal binding sites
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