2jvw: Difference between revisions

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[[Image:2jvw.gif|left|200px]]


{{Structure
==Solution NMR structure of uncharacterized protein Q5E7H1 from Vibrio fischeri. Northeast Structural Genomics target VfR117==
|PDB= 2jvw |SIZE=350|CAPTION= <scene name='initialview01'>2jvw</scene>
<StructureSection load='2jvw' size='340' side='right'caption='[[2jvw]]' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[2jvw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Aliivibrio_fischeri_ES114 Aliivibrio fischeri ES114]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JVW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JVW FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
|GENE= VF0530 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=312309 Vibrio fischeri ES114])
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jvw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jvw OCA], [https://pdbe.org/2jvw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jvw RCSB], [https://www.ebi.ac.uk/pdbsum/2jvw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jvw ProSAT], [https://www.topsan.org/Proteins/NESGC/2jvw TOPSAN]</span></td></tr>
}}
</table>
== Function ==
[https://www.uniprot.org/uniprot/DNABP_ALIF1 DNABP_ALIF1] Binds double-stranded DNA (dsDNA).<ref>PMID:21905121</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jv/2jvw_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jvw ConSurf].
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
Protein domain family PF09905 (DUF2132) is a family of small domains of unknown function that are conserved in a wide range of bacteria. Here we describe the solution NMR structure of the 80-residue VF0530 protein from Vibrio fischeri, the first structural representative from this protein domain family. We demonstrate that the structure of VF0530 adopts a unique four-helix motif that shows some similarity to the C-terminal double-stranded DNA (dsDNA) binding domain of RecA, as well as other nucleic acid binding domains. Moreover, gel shift binding data indicate a potential dsDNA binding role for VF0530. Proteins 2011; (c) 2011 Wiley-Liss, Inc.


'''Solution NMR structure of uncharacterized protein Q5E7H1 from Vibrio fischeri. Northeast Structural Genomics target VfR117'''
Solution NMR structure of VF0530 from Vibrio fischeri reveals a nucleic acid-binding function.,Aramini JM, Rossi P, Fischer M, Xiao R, Acton TB, Montelione GT Proteins. 2011 Oct;79(10):2988-91. doi: 10.1002/prot.23121. Epub 2011 Aug, 26. PMID:21905121<ref>PMID:21905121</ref>


 
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
==About this Structure==
</div>
2JVW is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Vibrio_fischeri_es114 Vibrio fischeri es114]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JVW OCA].
<div class="pdbe-citations 2jvw" style="background-color:#fffaf0;"></div>
[[Category: Single protein]]
== References ==
[[Category: Vibrio fischeri es114]]
<references/>
[[Category: Acton, T B.]]
__TOC__
[[Category: Aramini, J M.]]
</StructureSection>
[[Category: Baran, M C.]]
[[Category: Aliivibrio fischeri ES114]]
[[Category: Liu, J.]]
[[Category: Large Structures]]
[[Category: Montelione, G T.]]
[[Category: Acton TB]]
[[Category: NESG, Northeast Structural Genomics Consortium.]]
[[Category: Aramini JM]]
[[Category: Nwosu, C.]]
[[Category: Baran MC]]
[[Category: Owens, L A.]]
[[Category: Liu J]]
[[Category: Rossi, P.]]
[[Category: Montelione GT]]
[[Category: Rost, B.]]
[[Category: Nwosu C]]
[[Category: Swapna, G V.T.]]
[[Category: Owens LA]]
[[Category: Wang, D.]]
[[Category: Rossi P]]
[[Category: Xiao, R.]]
[[Category: Rost B]]
[[Category: alpha helical protein]]
[[Category: Swapna GVT]]
[[Category: nesg]]
[[Category: Wang D]]
[[Category: northeast structural genomics consortium]]
[[Category: Xiao R]]
[[Category: protein structure initiative]]
[[Category: psi-2]]
[[Category: solution nmr structure]]
[[Category: structural genomic]]
[[Category: unknown function]]
 
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Retrieved from "https://proteopedia.org/2jvw"