2kr9: Difference between revisions

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{{Seed}}
[[Image:2kr9.jpg|left|200px]]


<!--
==Kalirin DH1 NMR structure==
The line below this paragraph, containing "STRUCTURE_2kr9", creates the "Structure Box" on the page.
<StructureSection load='2kr9' size='340' side='right'caption='[[2kr9]]' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2kr9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KR9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KR9 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kr9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kr9 OCA], [https://pdbe.org/2kr9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kr9 RCSB], [https://www.ebi.ac.uk/pdbsum/2kr9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kr9 ProSAT]</span></td></tr>
{{STRUCTURE_2kr9|  PDB=2kr9  |  SCENE=  }}
</table>
 
== Function ==
===Kalirin DH1 NMR structure===
[https://www.uniprot.org/uniprot/KALRN_RAT KALRN_RAT] Promotes the exchange of GDP by GTP. Activates specific Rho GTPase family members, thereby inducing various signaling mechanisms that regulate neuronal shape, growth, and plasticity, through their effects on the actin cytoskeleton. Induces lamellipodia independent of its GEF activity. Isoforms 1 and 7 are necessary for neuronal development and axonal outgrowth. Isoform 6 is required for dendritic spine formation.<ref>PMID:10692441</ref> <ref>PMID:11606631</ref> <ref>PMID:15950621</ref>
 
== References ==
 
<references/>
==About this Structure==
__TOC__
2KR9 is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KR9 OCA].  
</StructureSection>
[[Category: Non-specific serine/threonine protein kinase]]
[[Category: Large Structures]]
[[Category: Rattus norvegicus]]
[[Category: Rattus norvegicus]]
[[Category: Gorbatyuk, V Y.]]
[[Category: Gorbatyuk VY]]
[[Category: Hoch, J C.]]
[[Category: Hoch JC]]
[[Category: Schiller, M R.]]
[[Category: Schiller MR]]
[[Category: Cytoskeleton]]
[[Category: Dbl-family gef]]
[[Category: Disulfide bond]]
[[Category: Guanine-nucleotide releasing factor]]
[[Category: Immunoglobulin domain]]
[[Category: Kinase]]
[[Category: Rho gtpase gef]]
[[Category: Transferase]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Dec 15 08:37:59 2010''

Latest revision as of 09:51, 9 May 2024

Kalirin DH1 NMR structure

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