6ez3: Difference between revisions
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==Structure of CDPS from Staphylococcus haemolyticus== | ==Structure of CDPS from Staphylococcus haemolyticus== | ||
<StructureSection load='6ez3' size='340' side='right' caption='[[6ez3]], [[Resolution|resolution]] 3.00Å' scene=''> | <StructureSection load='6ez3' size='340' side='right'caption='[[6ez3]], [[Resolution|resolution]] 3.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[6ez3]] is a 6 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6EZ3 OCA]. For a <b>guided tour on the structure components</b> use [ | <table><tr><td colspan='2'>[[6ez3]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_haemolyticus_JCSC1435 Staphylococcus haemolyticus JCSC1435]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6EZ3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6EZ3 FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6ez3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ez3 OCA], [https://pdbe.org/6ez3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6ez3 RCSB], [https://www.ebi.ac.uk/pdbsum/6ez3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6ez3 ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/CDLS_STAHJ CDLS_STAHJ] It uses activated amino acids in the form of aminoacyl-tRNAs (aa-tRNAs) as substrates to catalyze the ATP-independent formation of cyclodipeptides which are intermediates in diketopiperazine (DKP) biosynthetic pathways. Catalyzes the formation of cyclo(L-Leu-L-Leu) (cLL) from L-leucyl-tRNA(Leu). Can incorporate various nonpolar residues, such as L-phenylalanine, L-leucine and L-methionine, into cyclodipeptides.<ref>PMID:19430487</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: | [[Category: Large Structures]] | ||
[[Category: | [[Category: Staphylococcus haemolyticus JCSC1435]] | ||
[[Category: | [[Category: Bourgeois G]] | ||
[[Category: | [[Category: Mechulam Y]] | ||
[[Category: | [[Category: Schmitt E]] | ||