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[[Image:1wir.png|left|200px]]


{{STRUCTURE_1wir|  PDB=1wir  |  SCENE=  }}
==Solution structure of the C2H2 zinc finger domain of the protein arginine N-methyltransferase 3 from Mus musculus==
 
<StructureSection load='1wir' size='340' side='right'caption='[[1wir]]' scene=''>
===Solution structure of the C2H2 zinc finger domain of the protein arginine N-methyltransferase 3 from Mus musculus===
== Structural highlights ==
 
<table><tr><td colspan='2'>[[1wir]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WIR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1WIR FirstGlance]. <br>
 
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
==About this Structure==
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
[[1wir]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1WIR OCA].  
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1wir FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1wir OCA], [https://pdbe.org/1wir PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1wir RCSB], [https://www.ebi.ac.uk/pdbsum/1wir PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1wir ProSAT], [https://www.topsan.org/Proteins/RSGI/1wir TOPSAN]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/ANM3_MOUSE ANM3_MOUSE] Methylates (mono and asymmetric dimethylation) the guanidino nitrogens of arginyl residues in some proteins (By similarity).
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wi/1wir_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1wir ConSurf].
<div style="clear:both"></div>
__TOC__
</StructureSection>
[[Category: Large Structures]]
[[Category: Mus musculus]]
[[Category: Mus musculus]]
[[Category: Inoue, M.]]
[[Category: Inoue M]]
[[Category: Kigawa, T.]]
[[Category: Kigawa T]]
[[Category: Koshiba, S.]]
[[Category: Koshiba S]]
[[Category: Miyamoto, K.]]
[[Category: Miyamoto K]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Tomizawa T]]
[[Category: Tomizawa, T.]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S.]]
[[Category: C2h2 zinc finger domain]]
[[Category: Prmt3]]
[[Category: Protein arginine n-methyltransferase 3]]
[[Category: Riken structural genomics/proteomics initiative]]
[[Category: Rsgi]]
[[Category: Structural genomic]]
[[Category: Transferase]]