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==High resolution structure of acidic fibroblast growth factor. Mutant FGF-4-ALA-(24-154), 24 NMR structures==
==High resolution structure of acidic fibroblast growth factor. Mutant FGF-4-ALA-(24-154), 24 NMR structures==
<StructureSection load='1dzc' size='340' side='right' caption='[[1dzc]], [[NMR_Ensembles_of_Models | 24 NMR models]]' scene=''>
<StructureSection load='1dzc' size='340' side='right'caption='[[1dzc]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1dzc]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DZC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1DZC FirstGlance]. <br>
<table><tr><td colspan='2'>[[1dzc]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1DZC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1DZC FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2afg|2afg]], [[1axm|1axm]], [[2axm|2axm]], [[1rml|1rml]], [[1dzd|1dzd]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1dzc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dzc OCA], [http://pdbe.org/1dzc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1dzc RCSB], [http://www.ebi.ac.uk/pdbsum/1dzc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1dzc ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1dzc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1dzc OCA], [https://pdbe.org/1dzc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1dzc RCSB], [https://www.ebi.ac.uk/pdbsum/1dzc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1dzc ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/FGF1_HUMAN FGF1_HUMAN]] Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.<ref>PMID:8663044</ref> <ref>PMID:16597617</ref> <ref>PMID:20145243</ref>
[https://www.uniprot.org/uniprot/FGF1_HUMAN FGF1_HUMAN] Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.<ref>PMID:8663044</ref> <ref>PMID:16597617</ref> <ref>PMID:20145243</ref>  
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</div>
</div>
<div class="pdbe-citations 1dzc" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1dzc" style="background-color:#fffaf0;"></div>
==See Also==
*[[Fibroblast growth factor 3D structures|Fibroblast growth factor 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Cuevas, P]]
[[Category: Large Structures]]
[[Category: Gimenez-Gallego, G]]
[[Category: Cuevas P]]
[[Category: Gonzalez, C]]
[[Category: Gimenez-Gallego G]]
[[Category: Jimenez, M A]]
[[Category: Gonzalez C]]
[[Category: Lozano, R M]]
[[Category: Jimenez MA]]
[[Category: Pineda-Lucena, A]]
[[Category: Lozano RM]]
[[Category: Redondo-Horcajo, M]]
[[Category: Pineda-Lucena A]]
[[Category: Rico, M]]
[[Category: Redondo-Horcajo M]]
[[Category: Sanz, J M]]
[[Category: Rico M]]
[[Category: Antitumoral]]
[[Category: Sanz JM]]
[[Category: Cell cycle]]
[[Category: Growth factor]]
Retrieved from "https://proteopedia.org/1dzc"