2llk: Difference between revisions

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[[Image:2llk.jpg|left|200px]]


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==Solution NMR structure of the N-terminal myb-like 1 domain of the human cyclin-D-binding transcription factor 1 (hDMP1), Northeast Structural Genomics Consortium (NESG) target ID hr8011a==
The line below this paragraph, containing "STRUCTURE_2llk", creates the "Structure Box" on the page.
<StructureSection load='2llk' size='340' side='right'caption='[[2llk]]' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2llk]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LLK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LLK FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2llk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2llk OCA], [https://pdbe.org/2llk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2llk RCSB], [https://www.ebi.ac.uk/pdbsum/2llk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2llk ProSAT]</span></td></tr>
{{STRUCTURE_2llk|  PDB=2llk  |  SCENE=  }}
</table>
 
== Function ==
===Solution NMR structure of the N-terminal myb-like 1 domain of the human cyclin-D-binding transcription factor 1 (hDMP1), Northeast Structural Genomics Consortium (NESG) target ID hr8011a===
[https://www.uniprot.org/uniprot/DMTF1_HUMAN DMTF1_HUMAN] Transcriptional activator which activates the CDKN2A/ARF locus in response to Ras-Raf signaling, thereby promoting p53/TP53-dependent growth arrest (By similarity). Binds to the consensus sequence 5'-CCCG[GT]ATGT-3' (By similarity). Isoform 1 may cooperate with MYB to activate transcription of the ANPEP gene. Isoform 2 may antagonize transcriptional activation by isoform 1.<ref>PMID:12917399</ref>
 
== References ==
 
<references/>
==About this Structure==
__TOC__
[[2llk]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LLK OCA].  
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Arrowsmith, C.]]
[[Category: Large Structures]]
[[Category: Bellanda, M.]]
[[Category: Arrowsmith C]]
[[Category: Garcia, M.]]
[[Category: Bellanda M]]
[[Category: Houliston, S.]]
[[Category: Garcia M]]
[[Category: Lemak, A.]]
[[Category: Houliston S]]
[[Category: Min, J.]]
[[Category: Lemak A]]
[[Category: Montecchio, M.]]
[[Category: Min J]]
[[Category: Montelione, G T.]]
[[Category: Montecchio M]]
[[Category: NESG, Northeast Structural Genomics Consortium.]]
[[Category: Montelione GT]]
[[Category: SGC, Structural Genomics Consortium.]]
[[Category: Xu C]]
[[Category: Xu, C.]]
[[Category: Yee A]]
[[Category: Yee, A.]]
[[Category: Cell cycle]]
[[Category: Helix bundle]]
[[Category: Nesg]]
[[Category: Northeast structural genomics consortium]]
[[Category: Sgc]]
[[Category: Structural genomics consortium]]
[[Category: Transcription]]
Retrieved from "https://proteopedia.org/2llk"