2lw4: Difference between revisions
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New page: '''Unreleased structure''' The entry 2lw4 is ON HOLD Authors: Eletsky, A., Wang, D., Kohan, E., Janjua, H., Xiao, R., Acton, T.B., Everett, J.K., Montelione, G.T., Szyperski, T. Descri... |
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==Solution NMR Structure of Human Transcription Elongation Factor A protein 2, Central Domain, Northeast Structural Genomics Consortium (NESG) Target HR8682B== | |||
<StructureSection load='2lw4' size='340' side='right'caption='[[2lw4]]' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[2lw4]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2LW4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2LW4 FirstGlance]. <br> | |||
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2lw4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2lw4 OCA], [https://pdbe.org/2lw4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2lw4 RCSB], [https://www.ebi.ac.uk/pdbsum/2lw4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2lw4 ProSAT]</span></td></tr> | |||
</table> | |||
== Function == | |||
[https://www.uniprot.org/uniprot/TCEA2_HUMAN TCEA2_HUMAN] Necessary for efficient RNA polymerase II transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by S-II allows the resumption of elongation from the new 3'-terminus.<ref>PMID:12034815</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Homo sapiens]] | |||
[[Category: Large Structures]] | |||
[[Category: Acton TB]] | |||
[[Category: Eletsky A]] | |||
[[Category: Everett JK]] | |||
[[Category: Janjua H]] | |||
[[Category: Kohan E]] | |||
[[Category: Montelione GT]] | |||
[[Category: Szyperski T]] | |||
[[Category: Wang D]] | |||
[[Category: Xiao R]] | |||
Latest revision as of 05:53, 15 May 2024
Solution NMR Structure of Human Transcription Elongation Factor A protein 2, Central Domain, Northeast Structural Genomics Consortium (NESG) Target HR8682B
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