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==Solution NMR Structure of the OCRE Domain of RBM10==
==Solution NMR Structure of the OCRE Domain of RBM10==
<StructureSection load='2mxw' size='340' side='right' caption='[[2mxw]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
<StructureSection load='2mxw' size='340' side='right'caption='[[2mxw]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2mxw]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MXW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2MXW FirstGlance]. <br>
<table><tr><td colspan='2'>[[2mxw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2MXW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2MXW FirstGlance]. <br>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2mxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mxw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2mxw RCSB], [http://www.ebi.ac.uk/pdbsum/2mxw PDBsum]</span></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2mxw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2mxw OCA], [https://pdbe.org/2mxw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2mxw RCSB], [https://www.ebi.ac.uk/pdbsum/2mxw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2mxw ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
[[http://www.uniprot.org/uniprot/RBM10_HUMAN RBM10_HUMAN]] TARP syndrome. TARP syndrome (TARPS) [MIM:[http://omim.org/entry/311900 311900]]: A disorder characterized by the Robin sequence (micrognathia, glossoptosis and cleft palate), talipes equinovarus and cardiac defects. Note=The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:20451169</ref>
[https://www.uniprot.org/uniprot/RBM10_HUMAN RBM10_HUMAN] TARP syndrome. TARP syndrome (TARPS) [MIM:[https://omim.org/entry/311900 311900]: A disorder characterized by the Robin sequence (micrognathia, glossoptosis and cleft palate), talipes equinovarus and cardiac defects. Note=The disease is caused by mutations affecting the gene represented in this entry.<ref>PMID:20451169</ref>  
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/RBM10_HUMAN RBM10_HUMAN]] May be involved in post-transcriptional processing, most probably in mRNA splicing. Binds to RNA homopolymers, with a preference for poly(G) and poly(U) and little for poly(A) (By similarity).<ref>PMID:18315527</ref>
[https://www.uniprot.org/uniprot/RBM10_HUMAN RBM10_HUMAN] May be involved in post-transcriptional processing, most probably in mRNA splicing. Binds to RNA homopolymers, with a preference for poly(G) and poly(U) and little for poly(A) (By similarity).<ref>PMID:18315527</ref>  
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Geralt, M]]
[[Category: Homo sapiens]]
[[Category: Structural genomic]]
[[Category: Large Structures]]
[[Category: Martin, B T]]
[[Category: Geralt M]]
[[Category: Serrano, P]]
[[Category: Martin BT]]
[[Category: Wuthrich, K]]
[[Category: Serrano P]]
[[Category: Jcsg]]
[[Category: Wuthrich K]]
[[Category: Ocre domain]]
[[Category: Psi-biology]]
[[Category: Rbm10]]
[[Category: Unknown function]]