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==HIGH-RESOLUTION SOLUTION STRUCTURE OF FREE RGS4 BY NMR==
==HIGH-RESOLUTION SOLUTION STRUCTURE OF FREE RGS4 BY NMR==
<StructureSection load='1ezy' size='340' side='right'caption='[[1ezy]], [[NMR_Ensembles_of_Models | 30 NMR models]]' scene=''>
<StructureSection load='1ezy' size='340' side='right'caption='[[1ezy]]' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1ezy]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Buffalo_rat Buffalo rat]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EZY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1EZY FirstGlance]. <br>
<table><tr><td colspan='2'>[[1ezy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EZY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EZY FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1ezt|1ezt]]</td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1ezy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ezy OCA], [http://pdbe.org/1ezy PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1ezy RCSB], [http://www.ebi.ac.uk/pdbsum/1ezy PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1ezy ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1ezy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1ezy OCA], [https://pdbe.org/1ezy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1ezy RCSB], [https://www.ebi.ac.uk/pdbsum/1ezy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1ezy ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/RGS4_RAT RGS4_RAT]] Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(z)-alpha is inhibited by phosphorylation of the G-protein. Activity on G(z)-alpha and G(i)-alpha-1 is inhibited by palmitoylation of the G-protein.  
[https://www.uniprot.org/uniprot/RGS4_RAT RGS4_RAT] Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Activity on G(z)-alpha is inhibited by phosphorylation of the G-protein. Activity on G(z)-alpha and G(i)-alpha-1 is inhibited by palmitoylation of the G-protein.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
*[[Regulator of G protein signaling|Regulator of G protein signaling]]
*[[Regulator of G-protein signaling 3D structures|Regulator of G-protein signaling 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Buffalo rat]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Chanda, P K]]
[[Category: Rattus norvegicus]]
[[Category: Cockett, M I]]
[[Category: Chanda PK]]
[[Category: Edris, W]]
[[Category: Cockett MI]]
[[Category: Jones, P G]]
[[Category: Edris W]]
[[Category: Mason, K]]
[[Category: Jones PG]]
[[Category: Moy, F J]]
[[Category: Mason K]]
[[Category: Powers, R]]
[[Category: Moy FJ]]
[[Category: Semus, S]]
[[Category: Powers R]]
[[Category: 4-helix bundle]]
[[Category: Semus S]]
[[Category: Free rgs4 nmr structure]]
[[Category: Signaling protein inhibitor]]
Retrieved from "https://proteopedia.org/1ezy"