1nya: Difference between revisions

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[[Image:1nya.png|left|200px]]


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==NMR SOLUTION STRUCTURE OF CALERYTHRIN, AN EF-HAND CALCIUM-BINDING PROTEIN==
The line below this paragraph, containing "STRUCTURE_1nya", creates the "Structure Box" on the page.
<StructureSection load='1nya' size='340' side='right'caption='[[1nya]]' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[1nya]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharopolyspora_erythraea Saccharopolyspora erythraea]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NYA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1NYA FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
{{STRUCTURE_1nya|  PDB=1nya  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1nya FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1nya OCA], [https://pdbe.org/1nya PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1nya RCSB], [https://www.ebi.ac.uk/pdbsum/1nya PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1nya ProSAT]</span></td></tr>
</table>
== Function ==
[https://www.uniprot.org/uniprot/CBP_SACER CBP_SACER]
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ny/1nya_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1nya ConSurf].
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== Publication Abstract from PubMed ==
The structure of calerythrin, a prokaryotic 20 kDa calcium-binding protein has been determined by solution NMR spectroscopy. Distance, dihedral angle, J coupling, secondary chemical shift, residual dipolar coupling and radius of gyration restraints reveal four EF-hand motifs arranged in a compact globular structure. A tight turn in the middle of the amino acid sequence brings the two halves, each comprising a pair of EF-hands, close together. The structural similarity between calerythrin and the eukaryotic sarcoplasmic calcium-binding proteins is notable.


===NMR SOLUTION STRUCTURE OF CALERYTHRIN, AN EF-HAND CALCIUM-BINDING PROTEIN===
NMR solution structure of calerythrin, an EF-hand calcium-binding protein from Saccharopolyspora erythraea.,Tossavainen H, Permi P, Annila A, Kilpelainen I, Drakenberg T Eur J Biochem. 2003 Jun;270(11):2505-12. PMID:12755706<ref>PMID:12755706</ref>


 
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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(as it appears on PubMed at http://www.pubmed.gov), where 12755706 is the PubMed ID number.
== References ==
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<references/>
{{ABSTRACT_PUBMED_12755706}}
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</StructureSection>
==About this Structure==
[[Category: Large Structures]]
1NYA is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Saccharopolyspora_erythraea Saccharopolyspora erythraea]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1NYA OCA].
 
==Reference==
NMR solution structure of calerythrin, an EF-hand calcium-binding protein from Saccharopolyspora erythraea., Tossavainen H, Permi P, Annila A, Kilpelainen I, Drakenberg T, Eur J Biochem. 2003 Jun;270(11):2505-12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12755706 12755706]
[[Category: Saccharopolyspora erythraea]]
[[Category: Saccharopolyspora erythraea]]
[[Category: Single protein]]
[[Category: Annila A]]
[[Category: Annila, A.]]
[[Category: Drakenberg T]]
[[Category: Drakenberg, T.]]
[[Category: Kilpelainen I]]
[[Category: Kilpelainen, I.]]
[[Category: Permi P]]
[[Category: Permi, P.]]
[[Category: Tossavainen H]]
[[Category: Tossavainen, H.]]
[[Category: Ef-hand]]
 
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