2e6r: Difference between revisions

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{{Seed}}
[[Image:2e6r.png|left|200px]]


<!--
==Solution structure of the PHD domain in SmcY protein==
The line below this paragraph, containing "STRUCTURE_2e6r", creates the "Structure Box" on the page.
<StructureSection load='2e6r' size='340' side='right'caption='[[2e6r]]' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2e6r]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E6R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2E6R FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-->
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
{{STRUCTURE_2e6r|  PDB=2e6r  |  SCENE=  }}
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2e6r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e6r OCA], [https://pdbe.org/2e6r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2e6r RCSB], [https://www.ebi.ac.uk/pdbsum/2e6r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2e6r ProSAT], [https://www.topsan.org/Proteins/RSGI/2e6r TOPSAN]</span></td></tr>
 
</table>
===Solution structure of the PHD domain in SmcY protein===
== Function ==
 
[https://www.uniprot.org/uniprot/KDM5D_HUMAN KDM5D_HUMAN] Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. May play a role in spermatogenesis.<ref>PMID:17320160</ref> <ref>PMID:17320162</ref> <ref>PMID:17351630</ref>
 
== Evolutionary Conservation ==
==About this Structure==
[[Image:Consurf_key_small.gif|200px|right]]
2E6R is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2E6R OCA].  
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/e6/2e6r_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2e6r ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: He, F.]]
[[Category: Large Structures]]
[[Category: Inoue, M.]]
[[Category: He F]]
[[Category: Kadirvel, S.]]
[[Category: Inoue M]]
[[Category: Kigawa, T.]]
[[Category: Kadirvel S]]
[[Category: Muto, Y.]]
[[Category: Kigawa T]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Muto Y]]
[[Category: Shirouzu, M.]]
[[Category: Shirouzu M]]
[[Category: Terada, T.]]
[[Category: Terada T]]
[[Category: Yokoyama, S.]]
[[Category: Yokoyama S]]
[[Category: National project on protein structural and functional analyse]]
[[Category: Nmr]]
[[Category: Nppsfa]]
[[Category: Phd domain]]
[[Category: Riken structural genomics/proteomics initiative]]
[[Category: Rsgi]]
[[Category: Structural genomic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Nov 16 17:59:51 2008''
Retrieved from "https://proteopedia.org/2e6r"