2k43: Difference between revisions

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{{Seed}}
[[Image:2k43.jpg|left|200px]]


<!--
==Acidic fibroblast growth factor solution structure in the FGF-1-C2A binary complex: key component in the fibroblast growthfactor non-classical pathway==
The line below this paragraph, containing "STRUCTURE_2k43", creates the "Structure Box" on the page.
<StructureSection load='2k43' size='340' side='right'caption='[[2k43]]' scene=''>
You may change the PDB parameter (which sets the PDB file loaded into the applet)
== Structural highlights ==
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
<table><tr><td colspan='2'>[[2k43]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K43 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K43 FirstGlance]. <br>
or leave the SCENE parameter empty for the default display.
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
-->
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k43 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k43 OCA], [https://pdbe.org/2k43 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k43 RCSB], [https://www.ebi.ac.uk/pdbsum/2k43 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k43 ProSAT]</span></td></tr>
{{STRUCTURE_2k43| PDB=2k43 |  SCENE= }}
</table>
== Function ==
[https://www.uniprot.org/uniprot/FGF1_HUMAN FGF1_HUMAN] Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro.<ref>PMID:8663044</ref> <ref>PMID:16597617</ref> <ref>PMID:20145243</ref>
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/k4/2k43_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2k43 ConSurf].
<div style="clear:both"></div>


===Acidic fibroblast growth factor solution structure in the FGF-1-C2A binary complex: key component in the fibroblast growthfactor non-classical pathway===
==See Also==
 
*[[Fibroblast growth factor 3D structures|Fibroblast growth factor 3D structures]]
 
== References ==
==About this Structure==
<references/>
2K43 is a 1 chain structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K43 OCA].
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Mohan, S K.]]
[[Category: Large Structures]]
[[Category: Yu, C.]]
[[Category: Mohan SK]]
[[Category: Acetylation]]
[[Category: Yu C]]
[[Category: Angiogenesis]]
[[Category: Beta barrel]]
[[Category: Developmental protein]]
[[Category: Differentiation]]
[[Category: Growth factor]]
[[Category: Heparin-binding]]
[[Category: Mitogen]]
[[Category: Polymorphism]]
[[Category: Protein transport]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jun  4 07:32:31 2009''
Retrieved from "https://proteopedia.org/2k43"