2yun: Difference between revisions

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[[Image:2yun.jpg|left|200px]]


{{Structure
==Solution structure of the SH3 domain of human Nostrin==
|PDB= 2yun |SIZE=350|CAPTION= <scene name='initialview01'>2yun</scene>
<StructureSection load='2yun' size='340' side='right'caption='[[2yun]]' scene=''>
|SITE=  
== Structural highlights ==
|LIGAND=  
<table><tr><td colspan='2'>[[2yun]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YUN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YUN FirstGlance]. <br>
|ACTIVITY=  
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
|GENE= NOSTRIN ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yun FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yun OCA], [https://pdbe.org/2yun PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yun RCSB], [https://www.ebi.ac.uk/pdbsum/2yun PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yun ProSAT], [https://www.topsan.org/Proteins/RSGI/2yun TOPSAN]</span></td></tr>
}}
</table>
 
== Function ==
'''Solution structure of the SH3 domain of human Nostrin'''
[https://www.uniprot.org/uniprot/NOSTN_HUMAN NOSTN_HUMAN] Multivalent adapter protein which may decrease NOS3 activity by inducing its translocation away from the plasma membrane.<ref>PMID:12446846</ref> <ref>PMID:16234328</ref> <ref>PMID:16807357</ref>
 
== Evolutionary Conservation ==
 
[[Image:Consurf_key_small.gif|200px|right]]
==About this Structure==
Check<jmol>
2YUN is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YUN OCA].  
  <jmolCheckbox>
    <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/yu/2yun_consurf.spt"</scriptWhenChecked>
    <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
    <text>to colour the structure by Evolutionary Conservation</text>
  </jmolCheckbox>
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2yun ConSurf].
<div style="clear:both"></div>
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Large Structures]]
[[Category: Abe, H.]]
[[Category: Abe H]]
[[Category: Inoue, M.]]
[[Category: Inoue M]]
[[Category: Kigawa, T.]]
[[Category: Kigawa T]]
[[Category: Koshiba, S.]]
[[Category: Koshiba S]]
[[Category: Miyamoto, K.]]
[[Category: Miyamoto K]]
[[Category: RSGI, RIKEN Structural Genomics/Proteomics Initiative.]]
[[Category: Tochio N]]
[[Category: Tochio, N.]]
[[Category: Yokoyama S]]
[[Category: Yokoyama, S.]]
[[Category: national project on protein structural and functional analyse]]
[[Category: nitric oxide synthase trafficker]]
[[Category: nppsfa]]
[[Category: protein transport]]
[[Category: riken structural genomics/proteomics initiative]]
[[Category: rsgi]]
[[Category: structural genomic]]
 
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 18:49:24 2008''
Retrieved from "https://proteopedia.org/2yun"