Complement C3: Difference between revisions

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*'''C3a''' is a mediator of local inflammatory processes.   
*'''C3a''' is a mediator of local inflammatory processes.   
*'''C3b''' binds covalently to cell surface carbohydrates or immune aggregates.   
*'''C3b''' binds covalently to cell surface carbohydrates or immune aggregates.   
*Breakdown of C3b generates the fragment '''C3d''' (residues 996-1287) which binds to antigens enhancing their uptake by B cells. 
*'''C3c''' is another C3b cleavage product residues: 23-664, 749-954, 1321-1663.<ref>PMID:11414361</ref>
*'''C3c''' is another C3b cleavage product residues: 23-664, 749-954, 1321-1663.<ref>PMID:11414361</ref>
*'''C3d''' is a fragment generated by C3b(residues 996-1287) which binds to antigens enhancing their uptake by B cells<ref>PMID:17337780</ref>.


<scene name='59/594590/Cv/2'>C3b α and β chains with protein CRIG and Ca+2 ion</scene>.
<scene name='59/594590/Cv/2'>C3b α and β chains with protein CRIG and Ca+2 ion</scene>.