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==CRYSTAL STRUCTURE OF THE GNA 3'-CTC(BR)UAGAG-2'==
 
<StructureSection load='2xc6' size='340' side='right' caption='[[2xc6]], [[Resolution|resolution]] 1.83&Aring;' scene=''>
==Crystal structure of the GNA 3'-CTC(Br)UAGAG-2'==
<StructureSection load='2xc6' size='340' side='right'caption='[[2xc6]], [[Resolution|resolution]] 1.83&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[2xc6]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XC6 OCA]. <br>
<table><tr><td colspan='2'>[[2xc6]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XC6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XC6 FirstGlance]. <br>
</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene><br>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.83&#8491;</td></tr>
<tr><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZAD:(S)-1-(2,3-DIHYDROXYPROPYL)-ADENINE'>ZAD</scene>, <scene name='pdbligand=ZBU:(S)-1-(2,3-DIHYDROXYPROPYL)-5-BROMO-URACIL'>ZBU</scene>, <scene name='pdbligand=ZCY:(S)-1-(2,3-DIHYDROXYPROPYL)-CYTOSINE'>ZCY</scene>, <scene name='pdbligand=ZGU:(S)-1-(2,3-DIHYDROXYPROPYL)-GUANINE'>ZGU</scene>, <scene name='pdbligand=ZTH:(S)-1-(2,3-DIHYDROXYPROPYL)-THYMINE'>ZTH</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZAD:(S)-1-(2,3-DIHYDROXYPROPYL)-ADENINE'>ZAD</scene>, <scene name='pdbligand=ZBU:(S)-1-(2,3-DIHYDROXYPROPYL)-5-BROMO-URACIL'>ZBU</scene>, <scene name='pdbligand=ZCY:(S)-1-(2,3-DIHYDROXYPROPYL)-CYTOSINE'>ZCY</scene>, <scene name='pdbligand=ZGU:(S)-1-(2,3-DIHYDROXYPROPYL)-GUANINE'>ZGU</scene>, <scene name='pdbligand=ZTH:(S)-1-(2,3-DIHYDROXYPROPYL)-THYMINE'>ZTH</scene></td></tr>
<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xc6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xc6 OCA], [https://pdbe.org/2xc6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xc6 RCSB], [https://www.ebi.ac.uk/pdbsum/2xc6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xc6 ProSAT]</span></td></tr>
<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xc6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xc6 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xc6 RCSB], [http://www.ebi.ac.uk/pdbsum/2xc6 PDBsum]</span></td></tr>
</table>
<table>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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On the Structure and Dynamics of Duplex GNA.,Johnson AT, Schlegel MK, Meggers E, Essen LO, Wiest O J Org Chem. 2011 Oct 7;76(19):7964-74. Epub 2011 Aug 30. PMID:21838272<ref>PMID:21838272</ref>
On the Structure and Dynamics of Duplex GNA.,Johnson AT, Schlegel MK, Meggers E, Essen LO, Wiest O J Org Chem. 2011 Oct 7;76(19):7964-74. Epub 2011 Aug 30. PMID:21838272<ref>PMID:21838272</ref>


From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
<div class="pdbe-citations 2xc6" style="background-color:#fffaf0;"></div>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Essen, L O.]]
[[Category: Large Structures]]
[[Category: Meggers, E.]]
[[Category: Synthetic construct]]
[[Category: Schlegel, M K.]]
[[Category: Essen L-O]]
[[Category: Glycol nucleic acid]]
[[Category: Meggers E]]
[[Category: Rna]]
[[Category: Schlegel MK]]
[[Category: Watson-crick base pair]]
Retrieved from "https://proteopedia.org/2xc6"