9ffd: Difference between revisions

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New page: '''Unreleased structure''' The entry 9ffd is ON HOLD Authors: Frydenvang, K., Hussain, S., Mirza, O.A. Description: STRUCTURE OF ALDO-KETO REDUCTASE 1C3 (AKR1C3) IN COMPLEX WITH AN INH...
 
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'''Unreleased structure'''


The entry 9ffd is ON HOLD
==STRUCTURE OF ALDO-KETO REDUCTASE 1C3 (AKR1C3) IN COMPLEX WITH AN INHIBITOR MEDS765==
 
<StructureSection load='9ffd' size='340' side='right'caption='[[9ffd]], [[Resolution|resolution]] 1.75&Aring;' scene=''>
Authors: Frydenvang, K., Hussain, S., Mirza, O.A.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[9ffd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=9FFD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=9FFD FirstGlance]. <br>
Description: STRUCTURE OF ALDO-KETO REDUCTASE 1C3 (AKR1C3) IN COMPLEX WITH AN INHIBITOR MEDS765
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.75&#8491;</td></tr>
[[Category: Unreleased Structures]]
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=9ffd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=9ffd OCA], [https://pdbe.org/9ffd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=9ffd RCSB], [https://www.ebi.ac.uk/pdbsum/9ffd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=9ffd ProSAT]</span></td></tr>
[[Category: Hussain, S]]
</table>
[[Category: Frydenvang, K]]
== Function ==
[[Category: Mirza, O.A]]
[https://www.uniprot.org/uniprot/AK1C3_HUMAN AK1C3_HUMAN] Catalyzes the conversion of aldehydes and ketones to alcohols. Catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ) and the oxidation of 9-alpha,11-beta-PGF2 to PGD2. Functions as a bi-directional 3-alpha-, 17-beta- and 20-alpha HSD. Can interconvert active androgens, estrogens and progestins with their cognate inactive metabolites. Preferentially transforms androstenedione (4-dione) to testosterone.
__TOC__
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Frydenvang K]]
[[Category: Hussain S]]
[[Category: Mirza OA]]
Retrieved from "https://proteopedia.org/9ffd"